
研究领域(方向):
药物分析新方法、新材料
中药质量控制
中药物质基础分析
个人及工作简历(个人受教育及工作经历):
2021.10至今,西安交通大学,药学院,副教授
2018.5-2021.9,西安交通大学,药学院,助理研究员
2012.9-2018.3,西安交通大学,药物分析学,博士
2008.9-2012.7,西安交通大学,药学专业,学士
主要科研项目
1.主持国家自然科学基金青年项目,基于水凝胶3D细胞培养的靶向α1A受体细胞仿生色谱法筛选姜黄中活性成分,24万元,2021.1-2023.12。
2.主持基本科研业务费,聚偕胺肟半互穿网络琼脂糖水凝胶复合材料的制备及其对中药重金属的脱除研究,10万元,2023.1-2025.12。
3.主持陕西省中医药管理局一般项目,靶向ACE2受体的活性成分发现及桔梗“药对”配伍关系研究,5万元,2025.1-2026.12。
4.主持横向项目,院内制剂临床应用再评价,180万元,2025.8-2026.12。
学术及科研成果、专利、论文
1.科研奖励
(1)王嗣岑;解笑瑜;卜羽思;胡琪;侯晓芳;包涛;魏芬;景王慧. 细胞膜仿生涂层关键技术及其在中药筛选中的应用,陕西省高等学校科学技术研究优秀成果奖一等奖,陕西省教育厅, 2023.
(2)魏芬. 2019陕西省青年科学家大会优秀论文奖二等奖,陕西省科学技术协会, 2019.
(3)张杰;卢闻;单媛媛;潘晓艳;代秉玲;李鹏飞;师亚玲;魏芬;司茹.陕西高等学校科学技术奖一等奖,陕西省教育厅, 2019.
(4)Wei Fen; Wang Sicen. Conference Series LLC Best Poster Award, Chromatography 2016 Organizing Committee,国际学术奖, 2016.
(5)指导学生张璐娜等获2025年第三十六届“腾飞杯”创新创业大赛优秀奖
2.授权专利
(1)魏芬;王嗣岑;景王慧;苟喜兰;包涛;侯晓芳;解笑瑜;郝旖;卜羽思;一种聚偕胺肟半互穿网络水凝胶膜的制备方法和应用, 2026-01-27,中国, 2024 1 0655524.8.
(2)侯晓芳;王嗣岑;魏芬;解笑瑜;景王慧;包涛;张景;一种测定凝血酶活性的微型电化学发光生物传感器、制备方法及应用, 2025-09-16,中国, CN202411410729.6.
(3)王嗣岑;魏芬;侯晓芳;解笑瑜;包涛;张杰;苟喜兰;崔萍.一种基于水凝胶的细胞固定相制备方法, 2023-01-03,中国, CN202010637989.2.
(4)王嗣岑;贺浪冲;黄静;张涛;张杰;李西玲;魏芬.一种基于微载体的细胞固定相及其制备方法, 2016-4-27,中国, ZL201310419338.6.
3.代表性论文
(1) Zhang Xiaxi;Wei Fen*; Wang Sicen*. Adsorption and catalytic degradation by CoFe2O4 coated on metal-organic - organic framework for the removal of 4-nitrophenol and 2,4-dichlorophenol, Separation and Purification Technology, 2025, 354(8): 129458.
(2)Wei Fen1; Gou Xilan1; Wang Sicen*. Immobilized cells on microcarriers for efficient andbiomimetic screening of active compounds acting on FGFR4 from Fructus evodiae, Journal of Pharmaceutical and Biomedical Analysis, 2024, 248: 116284.
(3) He Xiaoshuang; Zhang Meihui;Wei Fen*; Wang Sicen*. Affinity character analysis of magnolol and honokiol based on stepwise frontal analysis coupled with cell membrane chromatography, Journal of Chromatography B-analytical Technologies in the Biomedical and Life Sciences, 2023, 1229.
(4)Wei Fen; Wang Sicen*; Gou Xilan. A review for cell-based screening methods in drug discovery, Biophysics Reports, 2021, 7(6): 504-516.
(5)Wei Fen; Gou Xilan; Xu Xiao; Wang Sicen*; Bao Tao. Sensitive quantification of Liensinine alkaloid using a HPLC-MS/MS method and its application in microvolume rat plasma, Journal of Analytical Methods in Chemistry, 2021, 2021: 6629579.
(6)苟喜兰;魏芬*;王嗣岑.基于植物药的抗新型冠状病毒肺炎活性化合物研究进展.西北药学杂志, 2021, 36(6): 1038-1042.
(7)Wei Fen; Zhang Xiaxi; Cui Ping; Gou Xilan; Wang Sicen*. Cell-based 3D bionic screening by mimicking in vivo drug-receptor interaction environment, Journal of Materials Chemistry B, 2020, 9(3): 683-693.
(8)Wei Fen; He Xiaoshuang; Xu Ke; Wang Sicen*. Stepwise frontal analysis coupled with cell membrane chromatography for affinity screening and characterization analysis of bioactive constituent from the mature fruits of schisandra chinensis, Journal of Chromatography B, 2020, 1161: 122443.
(9)Wei Fen; Wang Sicen; Lv Nan; Bu Yusi; Xie Xiaoyu*. Characterization the affinity of alpha(1A) adrenoreceptor by cell membrane chromatography with frontal analysis and stoichiometric displacement model, Journal of Chromatography B-Analytical Technologies in the Biomedical andLife Sciences, 2017, 1040(1): 273-281.
(10)Wei Fen; Hu Qi; Huang Jing; Han Shengli*; Wang Sicen.Screening active compounds from Corydalis yanhusuo by combining high expression VEGF receptor HEK293 cell membrane chromatography with HPLC - ESI - IT - TOF - MSn method. Journal of Pharmaceutical and Biomedical Analysis, 2017, 136: 134-139.
联系方式
电子邮箱:weifen.91@xjtu.edu.cn
联系电话:13227876326
个人主页:无
联系地址:陕西省西安市雁塔区,雁塔西路76号