马维娜

研究领域（方向）：

细胞膜色谱创新型技术研究与应用

药物-受体相互作用研究

抗肿瘤药物筛选与机制研究

个人及工作简历

科研项目：

学术及科研成果、专利、论文：

[1]Weina Ma,Cheng Wang, Rui Liu, Nan Wang, Yanni Lv, Bingling Dai, Langchong He*. Advances in cell membrane chromatography. Journal of Chromatography A, 2021,1639:461916.

[2]Weina Ma, Jingjing Sun, Jieni Xu, Zhangyi Luo, Dingwei Diao, Ziqian Zhang, Patrick J. Oberly, Margaret Beth Minnigh, Wen Xie, Samuel M Poloyac, Yi Huang, Song Li*. Sensitizing Triple Negative Breast Cancer to Tamoxifen Chemotherapy via a Redox-Responsive Vorinostat-containing Polymeric Prodrug Nanocarrier. Theranostics. 2020, 10(6):2463-2478.

[3] Man Zhu, Liu Yang, Xianpeng Shi, Zhengyan Gong, Runze Yu, Dongdong Zhang, Yanmin Zhang,Weina Ma*. TPD7 inhibits the growth of cutaneous T cell lymphoma H9 cell through regulating IL-2R signalling pathway. Journal of Cellular and Molelular Medicine. 2020, 24(1):984-995.

[4] Man Zhu, Yuxin Cui, Liu Yang, Tianfeng Yang, Hongying Wang, Dongdong Zhang,Weina Ma*, Yanmin Zhang*. Ephrin type-B receptor 4 affinity chromatography: An effective and rapid method studying the active compounds targeting Ephrin type-B receptor 4. Journal of Chromatography A, 2019,1586:82-90.

[5] Liu Yang, Yingnan Zeng, Nan Ma,Weina Ma*. Interaction of Taspine Derivative TPD7 with Vascular Endothelial Growth Factor Receptor 2 by Cell Membrane Chromatography. Chromatographia, 2019, 82:1741-1748.

[6]Weina Ma, Liu Yang, Langchong He*. Overview of the detection methods for equilibrium dissociation constant KD of drug-receptor interaction. Journal of Pharmaceutical Analysis, 2018, 8(3):147-152.

[7]Weina Ma, Liu Yang, Yanni Lv, Jia Fu, Yanmin Zhang, Langchong He*. Determine equilibrium dissociation constant of drug-membranereceptor affinity using the cell membrane chromatography relativestandard method. Journal of Chromatography A, 2017, 1503:12-20.

[8]Weina Ma, Man Zhu, Dongdong Zhang, Liu Yang, Tianfeng Yang, Xin Li, Yanmin Zhang*. Berberine inhibits the proliferation and migration of breast cancer ZR-75-30 cells by targeting Ephrin-B2. Phytomedicine, 2017, 25:45-51.

[9]Weina Ma, Man Zhu, Liu Yang, Tianfeng Yang, Yanmin Zhang*. Synergistic Effect of TPD7 and Berberine against Leukemia Jurkat Cell Growth through Regulating Ephrin-B2 Signaling. Phytotherapy Research, 2017, 31:1392-1399.

[10] Liu Yang, Man Zhu, Yuan Kang, Tianfeng Yang,Weina Ma*. Investigation of the binding characteristics between ligands and epidermal growth factor receptor by cell membrane chromatography. Journal of Molecular Recognition, 2018, 31:e2701.

[11]Weina Ma, Dongdong Zhang, Lei Zheng, Yingzhuan Zhan, Yanmin Zhang^*. Potential roles of Centipede Scolopendra extracts as a strategy against EGFR-dependent cancers. American Journal of Translational Research, 2015, 7(1): 39-52.

[12]Weina Ma, Dongdong Zhang, Jing Li, Delu Che, Rui Liu, Jie Zhang, Yanmin Zhang^*. Interactions between histamine H1 receptor and its antagonists by using cell membrane chromatography method. Journal of Pharmacy and Pharmacology, 2015, 67:1567-1574.

[13]Weina Ma, Yanmin Zhang, Jing Li, Rui Liu, Delu Che, Langchong He^*. Analysis of drug interactions with dopamine receptor by frontal analysis and cell membrane chromatography. Chromatographia, 2015, 78: 649–654.

[14]Weina Ma, Rui Liu, Junpeng Qi, Yanmin Zhang^*. Extracts of centipede Scolopendra subspinipes mutilans induce cell cycle arrest and apoptosis in A375 human melanoma cells. Oncology Letters, 2014, 8(1): 414-420.

[15]马维娜，何旭,郑蕾,张彦民^*.白藜芦醇对EGFR调控的肿瘤抑制作用及其机制.西安交通大学学报（医学版）, 2013, 2(34): 185 ~ 188.

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