罗肖,博士,西安交通大学基础医学院生理学与病理生理学系教授,博士研究生导师。
兼任陕西省生理科学会常务理事、陕西省预防医学会营养与食品安全专业委员会委员。
工作至今一直承担医学基础课程《生理学》、《机能实验学》、《高级医学研究英语实践》和医学宗濂班PBL的教学工作。参编人民卫生出版社等配套教材5部。
主要从事肥胖与糖尿病发病机制研究。发表学术论文40余篇,其中在国际高水平学术期刊《Brief Bioinform》、《Diabetes》、《J Nutr Biochem》、《Acta Physiologica》、《Mol Nutr Food Res》、《Mol Cell Endocrinol》等发表论文30余篇。主持国家自然科学基金项3项,中国博士后基金一等1项,中国博士后特别资助1项,陕西省自然科学基金1项,陕西省博士后基金二等1项,中央高校基本科研业务项目2项。指导大学生创新实验项目10项,指导大学生获全国基础医学实验设计大赛铜奖1项。2015年获张锡钧基金会优秀论文奖。
研究方向:1.肥胖及糖尿病的发病机制;2.围产代谢健康
招收硕士研究生学科
071000-01生理学
100104病理学与病理生理学
招收博士研究生学科
071003生理学
100104病理学与病理生理学
招收各相关专业推免生(可跨一级学科)和博士后
联系电话:86-29-82657490-805
E-mail:xluo@mail.xjtu.edu.cn
代表性论文:
Zhao Yang; Jianan Jiang; Yutian Tan; Guiying Yang; Miao Chen; Jiaqi Huang; Jing Liu; Xiaojing Wei; Siyao Wang;Xiao Luo*;Zhen Han*; Sexual dimorphism in thermogenic regulators and metrnl expression in adipose tissue of offspring mice exposed to maternal and postnatal overnutrition.J Physiol Biochem.2024 Accept.
Xiaojing Wei;Yutian Tan;Jiaqi Huang;Ximing Dong;Weijie Feng;Tanglin Liu;Zhao Yang;Guiying Yang;Xiao Luo*;N1-methylnicotinamide impairs gestational glucose tolerance in mice.J Mol Endocrinol. 2024 Jan 8;72(2):e230126.
Yuwei Zhang;Yifei Zhang;Yutian Tan;Xiao Luo*;Ru Jia*;Increased RBP4 and Asprosin Are Novel Contributors in Inflammation Process of Periodontitis in Obese Rats.Int J Mol Sci.2023 Nov 25;24(23):16739.
Xiaojing Wei;Chuanfei Wei;Yutian Tan;Ximing Dong;Zhao Yang;Jianqun Yan;Xiao Luo*; Both prolonged high-fat diet consumption and calorie restriction boost hepatic NAD+ metabolism in mice.J Nutr Biochem. 2023 May;115:109296.
Qing Song;Qingying Gao;Taotao Chen;Ting Wen;Peng Wu;Xiao Luo*;Qiaoyi Chen*; FAM3A Ameliorates Brain Impairment Induced by Hypoxia-Ischemia in Neonatal Rat.Cell Mol Neurobiol, 2023 Jan;43(1):251-264.
Chen Shen; Huiyu Li; Miao Li; Yu Niu; Jing Liu; Li Zhu; Hongsheng Gui; Wei Han; Huiying Wang; Wenpei Zhang; Xiaochen Wang;Xiao Luo*; Yu Sun*; Jiangwei Yan*; Fanglin Guan*; DLRAPom: a hybrid pipeline of Optimized XGBoost-guided integrative multiomics analysis for identifying targetable disease-related lncRNA–miRNA–mRNA regulatory axes.Briefings in Bioinformatics.2022;28(2): bbac046.
Zhao Yang;Jianan Jiang;Miao Chen;Jiaqi Huang;Jing Liu;Xiaojing Wei;Ru Jia;Lin Song;Bo Sun;Xiao Luo*;Qing Song*;Zhen Han*; Sex-Specific Effects of Maternal and Post-Weaning High-Fat Diet on Adipose Tissue Remodeling and Asprosin Expression in Mice Offspring.Mol Nutr Food Res.2022; 66(4):e2100470.
Ru Jia#;Xiaojing Wei#;Jianan Jiang;Zhao Yang;Jiaqi Huang;Jing Liu;Jianqun Yan;Xiao Luo*; NNMT is induced dynamically during beige adipogenesis in adipose tissues depot-specific manner.J Physiol Biochem.2022 Feb;78(1):169-183.
Xiaojing Wei;Ru Jia;Zhao Yang;Jianan Jiang;Jiaqi Huang;Jianqun Yan;Xiao Luo*; NAD+/sirtuin metabolism is enhanced in response to cold-induced changes in lipid metabolism in mouse liver.FEBS Lett.2020 Jun;594(11):1711-1725
Xiaojing Wei;Ru Jia;Guan Wang;Shangyu Hong;Lin Song;Bo Sun;Ke Chen;Nan Wang;Qiqi Wang;Xiao Luo*;Jianqun Yan*; Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction.J Nutr Biochem.2020 Jun;80:108377.
Xiao Luo#;Zhangya He#;Xiaomin Sun;Xinqian Gu;Wanyu Zhang;Jiayi Gao;Xiaomin Li;Ru Jia;Junxiang Wei;Yan Yu;Xiaoqin Luo*; DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model.Diabetes Metab Syndr Obes.2020 22;13:185-196.
Xiao Luo#;Ru Jia#;Xiaoqin Luo;Guan Wang;Qiangling Zhang;Hu Qiao;Nan Wang;Jianqun Yan*;Cold Exposure Differentially Stimulates Angiogenesis in BAT and WAT of Mice: Implication in Adrenergic Activation.Cell Physiol Biochem, 2017;42:974-986
Xiao Luo#;Ru Jia#;Qianglin Zhang;Bo Sun;Jianqun Yan*;Cold-Induced Browning Dynamically Alters the Expression Profiles of Inflammatory Adipokineswith Tissue Specificity in Mice.Int J Mol Sci,2016;17(5): 795-808
Xiaoqin Luo;Ru Jia; Qinyu Yao; Yirui Xu; Zhenyu Luo;Xiao Luo*; Nanping Wang*;Docosahexaenoic Acid Attenuates Adipose Tissue Angiogenesis and Insulin Resistance in High Fat Diet-fed Mid-aged Mice via a Sirt1-dependent Mechanism.Molecular Nutrition & Food Research, 2016; 60:871-885
Ru Jia; Xiaoqin Luo; Guan Wang; Caixia Lin; Hu Qiao; Nan Wang; Ting Yao; Johanna L. Barclay; Jonathan P. Whitehead;Xiao Luo*;Jianqun Yan*; Characterization of cold-induced remodeling reveals depot-specific differences across and within brown and white adipose tissues in mice.Acta Physiologica,2016; 217(4):311-24
Xiao Luo; Louise J. Hutley; Julie A. Webster; Yu-Hee Kim; Dong-Fang Liu; Felicity S. Newell; Charlotte H. Widberg; Anthony Bachmann; Nigel Turner; Carsten Schmitz-Peiffer; Johannes B. Prins; Gong-She Yang*; Jonathan P. Whitehead*; Identification of BAMBI as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors.Diabetes, 2012;61(1):124-136
主持项目:
项目名称 |
起止日期 |
项目来源(编号) |
金额(万元) |
主持人 |
DNMT1-NR4A3-UCP1轴调控脂肪组织功能:妊娠期糖尿病 子代性别差异性肥胖发生的新机制 |
2023.1-2026.12 |
国家自然科学基金项目 (82270900) |
52 |
罗肖 |
新的人LncRNA:lnc-GAT1调控妊娠期糖尿病患者脂肪组织慢性炎症反应的分子机制 |
2019.1-2022.12 |
国家自然科学基金项目(81871190) |
57 |
罗肖 |
利用基因敲除鼠模型研究BAMBI基因在脂肪细胞形成中的作用及分子机制 |
2013.1-2015.12 |
国家自然科学基金项目(31200886) |
23 |
罗肖 |
BAMBI在脂肪细胞形成中的生理学作用研究 |
2012.9-2014.9 |
西安交通大学基本科研业务费国际科技合作项目(2012jdhz61) |
4 |
罗肖 |
BAMBI缺失对小鼠棕色样脂肪细胞形成的影响及分子机制 |
2015.7-2017.7 |
中国博士后科学基金一等(2015M580856) |
8 |
罗肖 |
妊娠期糖尿病患者大网膜脂肪慢性炎症反应中的关键LncRNA功能及其调控机制研究 |
2016.1-2018.1 |
西安交通大学基本科研业务费综合交叉项目 (xjj2016089) |
10 |
罗肖 |
BAMBI在小鼠beige细胞定向与分化过程中的作用研究 |
2016.1-2017.12 |
陕西省自然科学基础研究计划-青年人才项目(2016JQ8021) |
3 |
罗肖 |
利用敲除鼠模型研究BAMBI基因在冷刺激诱导皮下脂肪血管生成中的作用及分子机制 |
2016.7-2017.7 |
陕西省博士后基金二等(2016BSHEDZZ86) |
2 |
罗肖 |
GDM患者OAT炎症反应中关键LncRNA功能研究 |
2017.7-2019.7 |
中国博士后科学基金特别资助(2017T100759) |
15 |
罗肖 |