李奇灵，博士研究生导师
研究领域（方向）：
妇科肿瘤，妇科内分泌
个人及工作简历：
2016/01-至今 西安交通大学第一附属医院妇产科，主任医师
2012/09-2016/01 西安交通大学第一附属医院妇产科，副主任医师
2010/09-2012/09美国Morehouse School of Medicine，博士后
2009/12-2010/09 西安交通大学第一附属医院妇产科，副主任医师
2006/07-2009/12 西安交通大学第一附属医院妇产科，主治医师
2003/09-2006/07第四军医大学，博士
2001/06-2003/09西安交通大学第一附属医院妇产科，主治医师
1998/07-2001/06西安医科大学一附院妇产科,住院医师
1995/09-1998/07西安医科大学，硕士
1994/07-1995/09吉林省前卫医院妇产科，住院医师
1989/09-1994/07白求恩医科大学，本科
科研项目：
[1]西安交通大学第一附属医院临床研究重点项目（XJTU1AF-CRF-2019-003）:子宫内膜癌筛查人工智能图像识别系统研究。
[2]陕西省技术创新引导专项基金(2019QYPY-138)：Li-Shi系统应用于子宫内膜癌筛查的多中心可行性研究。
[3]陕西省技术创新引导计划-产学研协同创新计划（2018XT-002）：Qi宫颈刷对于宫颈病变取样的可行性研究。
[4]陕西省重点研发计划-重点项目（2017ZDXM-SF-068）：利用一次性倒锥形双套管宫颈宫腔细胞刷建立子宫内膜癌筛查数据库。
[5]陕西省技术创新引导计划-产学研协同创新计划（2017XT-026）：两种不同子宫内膜细胞采集器对于诊断子宫内膜病变的自身对照临床研究。
[6]陕西省自然科学基础研究计划（2017ZDJC-11）：利用浆液性卵巢癌患者外周血肿瘤细胞DNA甲基化监测化疗耐药。
[7]西安交通大学基本科研业务费学科综合交叉类科研项目（xjj2015093）：七碳花菁-叶酸化合物的合成和肿瘤细胞染色研究。
[8]陕西省科技统筹创新工程计划重大科技成果转化引导专项项目（2014KTCG03-05）:一次性使用宫腔组织吸引管套装的研制开发及推广。
[9]西安交通大学第一附属医院临床研究课题（ XJTU1AH2014-007）：细胞采集器对于诊断子宫内膜病变的可行性研究。
[10]国家自然科学基金（81472823）：DNA 甲基化在预测卵巢癌耐药指导后续化疗中的机制研究。
10年内以第一作者或通讯作者发表SCI文章35篇（#为共同第一作者，*为通讯作者）：
[1]Min Li, Lanbo Zhao, Xue Zhou, Kailu Zhang, Panyue Yin, Yuliang Zou,Qiling Li*. Detection of carcinoma in serous effusions: a review. Am J Cancer Res, 2021,11(1):43-60 (IF=5.177)
[2] Lirui Zhang#, Lei Wang#, Lanbo Zhao, Yiran Wang, Kailu Zhang, Xue Feng, Xiaopeng Yan, Yi Lv,Qiling Li*.A prospective clinical trial using a magnetic anchoring internal grasper in gynecological laparoendoscopic single-site surgery. J Minim Invasive Gynecol. 2020 Oct 31:S1553-4650(20)31105-5 (IF=3.107)
[3] Xue Feng, Lu Han, Sijia Ma, Lanbo Zhao, Lei Wang, Kailu Zhang, Panyue Yin, Lin Guo, Wei Jing,Qiling Li*. Microbes in Tumoral in Situ Tissues and in Tumorigenesis. Front Cell Infect Microbiol. 2020 Nov 24; 10: 572570 (IF=4.123)
[4]Lu Han, Sijia Ma, Lanbo Zhao, Yiran Wang, Xue Feng, Kailu Zhang, Lei Wang, Shuhua Liu, Panyue Yin, Dongxin Liang, Huilian Hou, Guizhi Shi,Qiling Li*. Clinical evaluation of Li Brush endometrial samplers for diagnosing endometrial lesions in women with intrauterine devices. Front Med (Lausanne). 2020 Nov 30;7:598689 (IF=3.9)
[5] Shulan Lv#, Qing Wang#, Yan Li#, Lanbo Zhao, Yiran Wang, Xue Feng, Lu Han, Kailu Zhang, Panyue Yin, Huilian Hou, Guizhi Shi,Qiling Li*. A Clinical Comparative Study ofTwo Different Endometrial Cell Samplers in Evaluating Endometrial Lesions by Cytopathological Diagnosis, Cancer Management and Research, 2020,12:10551-10557 (IF=2.886)
[6]Yuliang Zou#, Xiaoqian Tuo#, Lei Wu, Yanli Liu, Xue Feng, Lanbo Zhao, Yiran Wang, Huilian Hou, Guizhi Shi,Qiling Li*. Comparison of cervical cytopathological diagnosis using an innovative Qi brush and traditional Cervex-Brush® Combi. Front Med, 2020, Jul 24;7:369 (IF=3.9)
[7] Yiran Wang, Lanbo Zhao, Xue Feng, Qing Li, Sijia Ma, Dongxin Liang, Mingge Liu, Panyue Yin andQiling Li*. Two-pronged treatment of hemoperitoneum and abnormal uterine bleeding in an adolescent girl with congenital fibrinogen deficiency: a case report and review of the literature. Front Med, 2020, 7:181(IF=3.9)
[8] Lanbo Zhao, Sijia Ma, Yiran Wang, Xue Feng, Jie Li, Qiuping Wang, Yawen Wang, Shuhua Liu,Qiling Li*. Accurate short tandem repeat analysis for confirmation of rare gestational adrenal choriocarcinoma: a case report. Transl Cancer Res, 2020, 9(5):3755-3761 (IF=0.986)
[9] Shulan Lv#, Rui Wang#, Xue Xue#, Lanbo Zhao, Xiaoqian Tuo, Sijia Ma, Dongxin Liang, Yiran Wang, Xue Feng, Qing Li, Qi Wang, Lu Han,Qiling Li*. SERM with estrogen does not affect the proliferation and apoptosis of uterine leiomyoma cells. Transl Cancer Res, 2020, 9(9):5390-5400 (IF=0.986)
[10]Qiling Li#*, Qi Wang#, Wei Xu#, Yamin Ma#, Qingwei Wang*, Danita Eatman, Shaojin You, Jin Zou, James Champion, Lanbo Zhao, Ye Cui, Wenzhi Li, Yangyang Deng, Li Ma, Biao Wu, Guangdi Wang, Xiaodong Zhang, Qing Wang, Mohamed A. Bayorh, Qing Song*. C-reactive protein causes adult-onset obesity through chronic inflammatory mechanism. Front. Cell Dev. Biol. 2020, Feb 20;8:18 (IF=5.201)
[11] Qi Wang#, Lanbo Zhao#, Lu Han#, Guoxing Fu, Xiaoqian Tuo, Sijia Ma, Qing Li,
Yiran Wang, Dongxin Liang, Miaomiao Tang, Chao Sun, Qing Wang, Qing Song,Qiling Li*. The differential distribution of bacteria between cancerous and noncancerous ovarian tissues in situ. Journal of Ovarian Research, 2020, Jan 18;13(1):8 (IF=2.989）
[12] Chao Sun#, Junkai Zou#, Lanbo Zhao, Qing Wang, Shaozhi Zhang, Qurat Ulain,
Qing Song,Qiling Li*. New doctor-patient communication learning software to help interns succeed in communication skills. BMC Med Educ. 2020 Jan 8;20(1):8 (IF=1.831)
[13] Qi Wang, Lanbo Zhao, Lu Han, Xiaoqian Tuo, Sijia Ma, Yiran Wang, Xue Feng, Dongxin Liang, Chao Sun, Qing Wang, Qing Song,Qiling Li*. The discordance of gene mutations between circulating tumor cells and Pprimary/metastatic Tumor. Mol Ther Oncolytics, 2019, Dec 20, 15:21-29 (SCI, IF=5.710)
[14] Xiaoqian Tuo, Lanbo Zhao, Qi Wang, Lu Han, Yiran Wang, Sijia Ma, Xue Feng, Qing Li, Chao Sun, Qing Wang, Guizhi Shi, Huilian Hou, Guanjun Zhang,Qiling Li*. Validation of molecular typing for endometrial screening test that predicts benign and malignant lesions.Front. Oncol. 2019 July 9; 9: 561(SCI, IF=4.137)
[15] Qing Wang, Qi Wang, Lanbo Zhao, Lu Han, Chao Sun, Sijia Ma, Huilian Hou, Qing Song, QilingLi*. Endometrial Cytology as a Method to Improve the Accuracy of Diagnosis of Endometrial Cancer: Case Report and Meta-Analysis. Front Oncol. 2019 Apr 24;9:256 (SCI, IF=4.137)
[16] Lu Han, Jiang Du, Lanbo Zhao, Chao Sun, Qi Wang, Xiaoqian Tuo, Huilian Hou, Yu Liu, Qing Wang, Qurat Ulain, Shulan Lv, Guanjun Zhang, Qing Song,Qiling Li*. An Efficacious Endometrial Sampler for Screening Endometrial Cancer. Front Oncol. 2019 Feb 19; 9:67 (SCI, IF=4.137)
[17] Qurat Ulain, Lu Han, Qian Wu, Lanbo Zhao, Qi Wang, Xiaoqian Tuo, Yiran Wang, Qing Wang, Sijia Ma, Chao Sun, Qing Song,Qiling Li*. Indocyanine green can stand alone in detecting sentinel lymph nodes in cervical cancer. J Int Med Res. 2018 Dec;46(12):4885-4897 (SCI, IF=1.351)
[18] Zhihua Ma, Lanbo Zhao, Na Xu, Chao Sun, Qi Wang, Yueling Wang,Qiling Li*, Qinrui Lu*.Secondary pregnancy by an implant in a laparoscopic trocar site: A case report.Medicine (Baltimore). 2018 May;97(18):e0534(SCI, IF=1.87)
[19] Shulan Lv, Rui Wang, Qi Wang, Lu Han, Xiaoqian Tuo, Huilian Hou, Yu Liu, Zan Shi, Qing Wang, Yan Li, Chao Sun, Xue Xue,Qiling Li*. A novel solution configuration on liquid-based endometrial cytology. PloS ONE, 2018, 13(2):e0190851 (SCI, IF=2.776)
[20] Chao Sun, Junkai Zou, Qing Wang, Qi Wang, Lu Han, Nasra Batchu, Qurat Ulain, Jiang Du, Shulan Lv, Qing Song,Qiling Li*. Review of the pathophysiology, diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor. J Int Med Res. 2018 Feb; 46(2): 663-674 (SCI, IF=1.351)
[21] Jiang Du, Yaling Li, Qing Wang, Nasra Batchu, Junkai Zou, Chao Sun, Shulan Lv, Qing Song,Qiling Li*. Sentinel lymph node mapping in gynecological oncology. Oncology Letters, 2017; 14: 7669-7675 (SCI, IF=1.664)
[22] Shulan Lv, Qing Wang, Wanqiu Zhao, Lu Han, Nasra Batchu, Qurat Ulain, Junkai Zou, Chao Sun, Jiang Du, Qing Song,Qiling Li*. A review of the postoperative lymphatic leakage. Oncotarget. 2017;8(40): 69062- 69075 (SCI, IF=5.168)
[23]Qiling Li*, Xue Xue, Wenzhi Li, Qi Wang, Lu Han, Tiffany Brunson, Wei Xu, Isfahan Chambers-Harris, Qing Wang, Xu Li, Li Ma, Qing Song*. Heterogeneous DNA methylation status in same-cell subpopulations of ovarian cancer tissues. Tumour Biol. 2017; 39(6): 1010428317701650 (SCI, IF=3.65)
[24] Zhongxue Ye, Junlong Wu, Qing Wang, Qi Wang, Lu Han, Qurat Ulain, Nasra Batchu, Qing Song,Qiling Li*. Perioperative administration of erythropoietin combined with iron sucrose in gynecological tumor patients: a retrospective study. Int J Clin Exp Med. 2017; 10(4): 7111-7116 (SCI, IF=0.833)
[25]Qiling Li*, Wei Xu, Xue Xue, Qi Wang, Lu Han, Wenzhi Li, Shulan Lv, Dong Liu, Jendai Richards, Zhujun Shen, Li Ma, Qing Song*. Presence of multimeric isoforms human C-reactive protein in tissues and blood. Mol Med Rep. 2016;14(6):5461-5466 (SCI,IF=1.692)
[26] Jiang Du, Yaling Li, Shulan Lv, Qing Wang, Chao Sun, Xin Dong, Ming He, Qurat Ulain, Yongxing Yuan, Xiaoqian Tuo, Nasra Batchu, Qing Song,Qiling Li*. Endometrial sampling devices for early diagnosis of endometrial lesions. J Cancer Res Clin Oncol. 2016; 142(12): 2515-2522 (SCI, IF=3.503)
[27] Yan-Xia Sui, Chao Sun, Shu-Lan Lv, Nasra Batchu, Jun-Kai Zou, Jiang Du, Qing Song,Qi-Ling Li*. Perineal leiomyoma in a postmenopausal woman: A case report. Oncol Lett. 2016; 12(3):2045-2047 (SCI, IF=1.39)
[28] Yueling Wang, Jiang Du, Shulan Lv, Yanxia Sui, Xue Xue, Chao Sun, Junkai Zou, Qunying Ma, Guoxing Fu, Qing Song,Qiling Li*. Vaginal implantation metastasis of endometrial carcinoma: A case report. Oncol Lett. 2016; 12(1): 513-515 (SCI, IF=1.39)
[29] Shulan Lv, Lili Xu, Nasra Batchu, Yuanyuan Wang, Rui Wang, Xue Xue, Qing Song,Qiling Li*. Hormone replacement therpay for a young woman with cervical carcinoma. Int J Exp Med. 2016; 9(7): 14808-14814 (SCI, IF=1.069)
[30]Qiling Li*, Wei Xu, Ye Cui, Li Ma, Jendai Richards, Wenzhi Li, Yamin Ma, Guoxing Fu, Tameka Bythwood, Yueling Wang, Xu Li & Qing Song*. A preliminary exploration on DNA methylation of transgene across generations in transgenic rats. Scientific Reports. 2015; 6;5:8292 (SCI, IF= 5.228)
[31]Qiling Li*, Min Li, Li Ma, Wenzhi Li, Xuehong Wu, Jendai Richards, Guoxing Fu, Tameka Bythwood, Xu Li, Jianxin Wang, Qing Song*. A Method to Evaluate Genome-wide Methylation in Archival Formalin-fixed, Paraffin-embedded Ovarian Epithelial Cells. PLoS One. 2014; 9(8):e104481 (SCI, IF=3.534)
[32] Yueling Wang#,Qiling Li#*, Huiping Du, Shulan Lv, Huiting Liu. Uterine prolapse complicated by vaginal cancer: a case report and literature review. Gynecol Obstet Invest. 2014;77(2):141-144 (SCI, IF=1.251)
[33]Qiling Li#, Yamin Ma#, Wenzhi Li, Wei Xu, Li Ma, Guoxing Fu, Xiaohua Tian, Yueling Wang, Xu Li, Tameka Bythwood, Jendai Richards, Mukaila A Akinbami, Qing Song*. A promoter that drives gene expression preferentially in male transgenic rats. Transgenic Res. 2014; 23(2):341-349 (SCI, IF=2.609)
[34]Qiling Li, Ting Kang, Xiaohua Tian, Yamin Ma, Min Li, Jendai Richards, Tameka Bythwood, Yue ling Wang, Xu Li, Dong Liu, Li Ma, Qing Song*. Multimeric stability of human C-reactive protein in archived specimens. PLoS One. 2013;8(3):e58094（SCI, IF=3.73）
[35]Qi-ling Li*, Shang-feng Gao, Yun-ping Wang, Jun Ma, Cai-xia Feng, Ying Wang, Yue-ling Wang. In vitro-activated tumor-bearing host T cells and the effectiveness of tumor vaccine immunotherapy. Ann Saudi Med; 2012;32(2): 162-168 (SCI, IF=1.071)
专利6项：
[1]使用新型专利：吕毅，李奇灵，孙超，赵蓝波，赵惊涛。一种带有通过磁压榨防播散举宫杯罩的举宫器，2019.6,中国，专利号：ZL2019 2 0828280.3。
[2]实用新型专利：李奇灵，孙超，赵蓝波。防粘连节育器，2017.9，中国，专利号：ZL2016 2 1272371.6。
[3]发明专利：李奇灵，赵蓝波。一种通过宫颈进入宫腔自动展开的防粘连器，2017.6，中国，专利号：201710488089.4。
[4]发明专利：李奇灵，吴彪，曹利平。用于靶向肿瘤组织的近红外线荧光染色剂及制备方法和应用，2015.3，中国，专利号：201510104185.5。
[5]实用新型专利：李奇灵，吕淑兰，薛雪，赵蓝波。一种一次性使用倒椎形双套管式宫颈宫腔细胞刷，2014.2,中国，专利号：ZL201420720356.8。
[6]实用新型专利：李奇灵。一次性宫颈钳，2012.2,中国，专利号：ZL201120228622.1。
论著及教材4部：
[1]人民卫生出版社国家医学教育题库（五年制临床医学专业版）《妇产科学》副主编，2021年第二版。
[2]参考书《子宫内膜癌筛查临床与病理》主编，人民卫生出版社，2020年第一版。
[3]科普教材《高龄二孩妈妈全攻略-专家解读》副主编，人民卫生出版社，2018年第一版。
[4]国家卫生和计划生育委员会“十二五”规划教材，全国高等医药教材建设研究会“十二五”规划教材，全国高等学校器官系统整合教材《女性生殖系统疾病》编委，2015年8月第一版，人民卫生出版社。
奖项4项：
[1]李奇灵，钟德星，赵惊涛。《Li-Shi-Zhong子宫内膜癌筛查人工智能辅助诊断系统》在“圆通杯”兰州大学2020年全球校友创新创业大赛中荣获银奖。
[2]《Li-Brush子宫内膜细胞采集器用于IUD女性子宫内膜病变筛查的可行性研究》被评为2019年西安交通大学优秀硕士学位论文，指导教师：李奇灵。
[3]李奇灵。《子宫内膜癌筛查》被评为2018年陕西省优秀科普微视频。
[4]李奇灵，西安交通大学2009年度“王宽诚育才奖”。
联系方式:
e-mail: liqilinglady@163.com
Add:西安市雁塔西路277号，西安交通大学第一附属医院妇产科（710061）
