研究领域（方向）:
围术期脑保护策略研究
个人及工作简历
马磊，西安交通大学第二附属医院麻醉科副主任医师，副研究员，麻醉学博士，生理学博士后，博士研究生导师。主要从事临床麻醉的医疗、教学及科研工作，擅长小儿麻醉及老年危重病人的管理。研究方向为围术期脑保护策略研究，主持国家自然科学基金青年科学基金项目1项，中国博士后科学基金面上项目1项，陕西省自然科学基础研究计划面上项目1项，西安交通大学第二附属医院人才培养专项科研基金1项，校级新技术新疗法项目1项。发表SCI论文13篇，其中以第一作者或通讯作者在Neuropharmacology (IF: 5.012) 和Sci Rep (IF: 5.578) 等杂志上发表SCI论文8篇。担任陕西省麻醉学会青年委员会副主委，西安市麻醉学会青年委员会副主委。
2020.01--至今 西安交通大学第二附属医院麻醉科，副主任医师
2019.06--至今 西安交通大学第二附属医院麻醉科，博士研究生导师
2019.01---至今 西安交通大学第二附属医院麻醉科，副研究员
2015.12--2019.12 第四军医大学生理学教研室，博士后
科研项目
1. 国家自然科学基金青年科学基金项目, 81601148, 2017/01-2019/12, 17万
2. 中国博士后科学基金面上项目, 2017M613349, 10万（博士后课题军队1:1配套，所列经费为总额）
3. 陕西省自然科学基础研究计划面上项目, 2018JM7087, 2018/01-2019/12, 3万
4. 西安交通大学第二附属医院人才培养专项科研基金, RC(XM)201707, 2018/01-2019/12, 4万
学术及科研成果、专利、论文
1. Ma L, Jia J, Niu W, Jiang T, Zhai Q, Yang L, Bai F, Wang Q, Xiong L. Mitochondrial CB1 receptor is involved in ACEA-induced protective effects on neurons and mitochondrial functions. Sci Rep. 2015 Jul 28;5:12440. (IF: 5.578)
2. Ma L, Niu W, Yang S, Tian J, Luan H, Cao M, Xi W, Tu W, Jia J, Lv J. Inhibition of mitochondrial permeability transition pore opening contributes to cannabinoid type 1 receptor agonist ACEA-induced neuroprotection. Neuropharmacology. 2018 Mar 21;135:211-222. (IF: 5.012)
3. Ma L, Niu W, Lv J, Jia J, Zhu M, Yang S. PGC-1α-mediated mitochondrial biogenesis is involved in cannabinoid receptor 2 agonist AM1241-induced microglial phenotype amelioration. Cell Mol Neurobiol. 2018 Nov;38(8):1529-1537. (IF: 3.895)
4. Ma L, Zhu Z, Zhao Y, Hou L, Wang Q, Xiong L, Zhu X, Jia J, Chen S. Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia. Curr Neurovasc Res. 2011 May;8(2):145-152. (IF: 3.047)
5. Ma L, Jia J, Liu X, Bai F, Wang Q, Xiong L. Activation of murine microglial N9 cells is attenuated through cannabinoid receptor CB2 signaling. Biochem Biophys Res Commun. 2015 Feb 27;458(1):92-7. (IF: 2.281)
6. Jia J, Ma L (co-first author), Wu M, Zhang L, Zhang X, Zhai Q, Jiang T, Wang Q, Xiong L. Anandamide Protects HT22 Cells Exposed to Hydrogen Peroxide by Inhibiting CB1 Receptor-Mediated Type 2 NADPH Oxidase. Oxid Med Cell Longev. 2014; 2014:893516. (IF: 3.363)
7. Niu W, Wang Y, Liu Y, Zhang B, Liu M, Luo Y, Zhao P, Zhang Y, Wu H1, Ma L (co-corresponding author), Li Z. Starch-derived absorbable polysaccharide hemostat enhances bone healing via BMP-2 protein. Acta Histochem. 2017 Apr;119(3):257-263. (IF: 1.347)
8. Niu W, Ma L (co-first author), Tao T, Tian F, He T, Qiao M, He H, Liu X, Zhao X. Surgery-induced cognitive dysfunction is alleviated through triggering receptor expressed on myeloid cells 2. Acta Histochem. 2020 Apr. (IF: 1.719)
9. Zhao Y, Chen X, Ma L, Zuo Z, Zhu Z, Zhu X, Wang Q, He E, Xiong L, Pei J, Xu L, Hou L, Chen S. Electroacupuncture pretreatment induces tolerance against focal cerebral ischemia through activation of canonical Notch pathway. BMC Neurosci. 2012 Sep 19;13:111.
10. Zhu X, Yin J, Li L, Ma L, Tan H, Deng J, Chen S, Zuo Z. Electroacupuncture preconditioning-induced neuroprotection may be mediated by glutamate transporter type 2. Neurochem Int. 2013 Oct;63(4):302-8.
11. Zhai Q, Li F, Chen X, Jia J, Sun S, Zhou D, Ma L, Jiang T, Bai F, Xiong L, Wang Q. Triggering Receptor Expressed on Myeloid Cells 2, a Novel Regulator of Immunocyte Phenotypes, Confers Neuroprotection by Relieving Neuroinflammation. Anesthesiology. 2017 Jul;127(1):98-110.
12. Du J, Wang Q, Hu B, Peng Z, Zhao Y, Ma L, Xiong L, Lu Y, Zhu X, Chen S. Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats. Brain Res. 2010 Nov 11;1360:1-7.
13. Guo F, Jiang T, Song W, Wei H, Wang F, Liu L, Ma L, Yin H, Wang Q, Xiong L. Electroacupuncture Attenuates Cerebral Ischemia-Reperfusion Injury in Diabetic Mice Through Adiponectin Receptor 1-Mediated Phosphorylation of GSK-3β. Mol Neurobiol. 2015 Apr;51(2):685-95.
联系方式
电子邮箱：malei0214@xjtu.edu.cn
联系地址：西安交通大学第二附属医院麻醉科
