刘鑫

姓名:

刘鑫

一级学科:

公共卫生与预防医学

照片:

     

3A1E0


研究领域(方向):

1. 营养与慢性病流行病学:心血管代谢性疾病的营养随机对照试验多组学精准营养干预研究,杂粮全谷物改善代谢健康的效果与机制。

2. 系统流行病学:基于大型人群队列、临床纵向队列,探讨基因、营养代谢组、宏基因组及在肥胖、2型糖尿病、高血压及心脑血管疾病等发生发展中所起的作用

3. 人类营养与全球健康。

个人及工作简历:

教育背景与工作经历:

2005-2009年,西北大学生命科学学院,学士

2009-2014年,中国科学院上海生命科学研究院营养科学研究所,博士

2014-2015年,贝因美临床营养研究中心,营养科学经理

2015-至今,西安交通大学公共卫生学院流行病与卫生统计学系,先后任讲师、副教授、教授

2016-2017年,牛津大学China Kadoorie Biobank组,访问学者

主要学术兼职:

Nutrition & Metabolism副主编

Asia Pacific Journal of Clinical Nutrition编委

中国营养学会基础营养学分会 副主任委员

中国营养学会营养与组学技术分会 常务委员

中华预防医学会行为健康分会 委员

陕西省营养学会 理事

主要科研项目

主持国家自然科学基金3项,含青年项目、面上项目、国家自然科学基金与英国皇家学会合作交流基金;主持营养BASF亚洲研究基金,汤臣倍健、飞鹤、帝斯曼、西麦及AB-biotics等多项企业研究基金

代表性论著、科研获奖、人才称号

慢性病队列研究成果:

1. Liu X, Bragg F, Yang L, Kartsonaki C, Guo, Du, H, Bian Z, Chen Y; Yu C, Lv J, Wang K, Zhang H, Chen J, Clarke R, Collins R, Peto R, Li L, Chen Z, The China Kadoorie Biobank Collaborative Group. Smoking and smoking cessation in relation to risk of diabetes in Chinese men and women: a 9-year prospective study of 0.5 million people. Lancet Public Health, 2018, Apr 3 (4), e167-e176, IF=50

2. Wang M, Xu K, Yang J, Bennett DA, Du H, Liu X*. Normal-weight obesity subtypes and 10-year risks of major vascular diseases in 0.3 million adults. Clin Nutr. 2024 Dec 27;45:36-42.. IF=6.6

3. Liu X, Lu L, Yao P, Ma Y, Wang F, Jin Q, Ye X, Hu F, Sun L, Lin X. Lipopolysaccharide binding protein, obesity status, and incidence of metabolic syndrome: a prospective study among middle-aged and older Chinese. Diabetologia. 2014 Sep;57(9):1834-41. IF=8.2

4. Xu K, Zhang B, Liu Y, Mi B, Wang Y, Shen Y, Shi G, Dang S, Liu X*, Yan H. Staple Food Preference and Obesity Phenotypes: The Regional Ethnic Cohort Study in Northwest China[J]. Nutrients, 2022, 14(24): 5243. IF=5.9

5. Liu X*, Lai H, Mi B, Qi X, Gan W, Du, H. Associations of Coarse Grain Intake with Undiagnosed Hypertension among Chinese Adults: Results from the China Kadoorie Biobank. Nutrients 2020, 12(12), 3814; https://doi.org/10.3390/nu12123814. IF=5.9

6. Ma G, Li J, Xie J, Li Y, Xu K, He Y, Yang J, Du H, Liu X*. Pulse pressure and its association with body composition among Chinese men and women without diagnosed hypertension: the China Kadoorie Biobank. J Hypertens. 2023 Nov 1;41(11):1802-1810. doi: 10.1097/HJH.0000000000003549. Epub 2023 Sep 6. PMID: 37682069. IF=4.9

营养随机对照试验成果:

1. Lai H, Li Y, He Y, Chen F, Mi B, Li J, Xie J, Ma G, Yang J, Xu K, Liao X, Yin Y, Liang J, Kong L, Wang X, Li Z, Shen Y, Dang S, Zhang L, Wu Q, Zeng L, Shi L, Zhang X*, Tian T*, Liu X*. Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial. Gut Microbes, 2023 Jan-Dec;15(1):2197837. doi: 10.1080/19490976.2023.2197837. IF=12.2

2. Ma G, Li Y, He C, Li J, Xie J, Alballa MM, Xu K, Feng X, He J, Jia K, He Y, Li W, Chen F, Mi B, Yang J, Yu H, Liao X, Zhang B, Yang N, Dong Q, Wang Q*, Ze X*, Liu X*. Effects of Lactiplantibacillus plantarum on moderate dyslipidemia before medication involving gut microbiota and host genetics. NPJ Sci Food. 2026 Feb 9. doi: 10.1038/s41538-026-00749-z. Epub ahead of print. PMID: 41663420. IF=7.8

3. Li J, He Y, He J, Xie J, He C, Jia K, Wang M, Li W, Feng X, Ma G, Tang A, Xu K, Niu H, Liao X, Yu H, Shi L, Li L, Si L, Chen F, Mi B, Tian T*, Liu X*. Tailored effects of coarse grain substitution on blood pressure via gut microbiota-metabolite networks and host gene variants: a randomized controlled trial. NPJ Sci Food. 2026 Jan 21;10(1):58. doi: 10.1038/s41538-026-00708-8. PMID: 41565707; PMCID: PMC12901048. IF=7.8

4. He Y, Xu K, Li Y, Chang H, Liao X, Yu H, Tian T, Li C, Shen Y, Wu Q, Liu X*, Shi L. Metabolomic changes upon conjugated linoleic acid supplementation and predictions of body composition responsiveness. J Clin Endocrinol Metab. 2022 Aug 18;107(9):2606-2615. doi: 10.1210/clinem/dgac367. PMID: 35704027. IF=5.8

5. Jia K, She Y, He Y, He J, He Y, Xu K, Ma G, Li W, He C, Feng X, Wang M, Tang A, Sun X, Kong L*, Liu X*. Conjugated Linoleic Acid Supplementation Suppresses the De Novo Lipogenesis in Adults With High Body Fat: A Double-Blind, Randomized, Placebo-Controlled Trial. Mol Nutr Food Res. 2025 Oct 30:e70306. doi: 10.1002/mnfr.70306. IF=4.9

6. Chang H, Gan W, Liao X, Wei J, Lu M, Chen H, Wang S, Ma Y, Wu Q, Yu Y*, Liu X*. Conjugated linoleic acid supplements preserve muscle in high-body-fat adults: a double-blind, randomized, placebo trial. Nutrition Metabolism and Cardiovascular Diseases.2020. https://doi.org/10.1016/j.numecd.2020.05.029 E-published ahead of print. IF=3.9

7. Liu X, Zhang G, Ye X, Li H, Chen X, Tang L, Feng Y, Shai I, Stampfer M, Hu F, Lin X. Effects of a low-carbohydrate diet on weight loss and cardiometabolic profile in Chinese women: a randomized controlled feeding trial. British Journal of Nutrition. 2013, (110), 1444-1453. IF=3.6

8. Li S, Mi B, Qu P, Liu D, Lei F, Wang D, Zeng L, Kang Y, Shen Y, Zhu Z, Yan H, Liu X*, Dang S. Association of antenatal vitamin B complex supplementation with neonatal vitamin B12 status: evidence from a cluster randomized controlled trial. European Journal of Nutrition. 2020 Jun 23. [Epub ahead of print]. IF=5.0

9. Ma Y, Sun Y, Sun L, Liu X, Zeng R*, Lin X*, & Li Y*. Effects of gut microbiota and fatty acid metabolism on dyslipidemia following weight-loss diets in women: results from a randomized controlled trial. Clinical Nutrition.2021 Sep 23. E-Published DOI:https://doi.org/10.1016/j.clnu.2021.09.021 IF=6.3

多组学代谢健康研究成果:

1. Wang M, Ma G, Li Y, Li J, Xie J, He J, He C, He Y, Jia K, Feng X, Tian T, Li H, Liao X*, Liu X*. Potential Modulatory Roles of Gut Microbiota and Metabolites in the Associations of Macronutrient-to-Physical Activity Ratios With Dyslipidemia. J Am Heart Assoc. 2025 May 20;14(10):e040042. doi: 10.1161/JAHA.124.040042. IF=5.0

2. Xu K, Shen Y, Shi L, Chen F, Zhang B, He Y, Wang Y, Liu Y, Shi G, Mi B, Zeng L, Dang S*, Liu X*, Yan H*. Lipidomic perturbations of normal-weight adiposity phenotypes and their mediations on diet-adiposity associations. Clin Nutr. 2024 Nov;43(11):20-30. doi: 10.1016/j.clnu.2024.09.020. Epub 2024 Sep 17. PMID: 39307096. IF=6.6

3. Xu K, Zhang B, He Y, Wang Y, Liu Y, Shi G, Shen Y, Chen F, Mi B, Shi L, Zeng L, Liu X*, Dang S*, Yan H*. Serum Lipidomic Signatures Mediate the Association Between Coarse Grain Preference and Central Obesity in Adults With Normal Weight and High Wheat Intake. Mol Nutr Food Res. 2025 Jan;69(1):e202400515. doi: 10.1002/mnfr.202400515. Epub 2024 Dec 18. PMID: 39692176. IF=4.9

4. He J, He Y, Li J, Ma G, Li Y, Xie J, He C, Feng X, Jia K, Li W, Wang M, Tang A, Tian T, Liao X, Li W, Yan F, Zhang Y, Cao X, Zhang Y, Yang N, Liu X*, Wang Q*. Habitual coarse grain intake, gut microbiota, and hyperuricemia in individuals with or at risk of metabolic syndrome: A post-hoc analysis. Nutr Metab Cardiovasc Dis. 2025 Oct;35(10):104126. doi: 10.1016/j.numecd.2025.104126. Epub 2025 May 11. PMID: 40447549.

5. Li W, Wang M, Xu K, He J, Feng X, Ma G, Li Y, Lai H, Tang A, He C, He Y, Jia K, Liao X, Yu H, Tian T, Liu X*. Coarse Grain Preference, Gut Microbiota Features, in Relation to Hypertriglyceridemia in Constipation Patients: A Cross-Sectional Study. Mol Nutr Food Res. 2025 Oct;69(19):e70155. doi: 10.1002/mnfr.70155. Epub 2025 Jun 16. PMID: 40522116. IF=4.9

6. Li J, Ma G, Xie J, Xu K, Lai H, Li Y, He Y, Yu H, Liao X, Wang X, Li Z, Kong L, Mi B, Shen Y, Tian T, Liu X*. Differential Gut Microbiota, Dietary Intakes in Constipation Patients with or without Hypertension. Mol Nutr Food Res. 2023 Sep 15:e2300208. doi: 10.1002/mnfr.202300208. Epub ahead of print. PMID: 37712107. IF=5.2

7. Yan T, Shi L*, Xu K, Bai J, Wen R, Liao X, Dai X, Wu Q, Zeng L, Peng W, Wang Y, Yan H, Dang S*, Liu X*, Habitual intakes of sugar-sweetened beverages associated with gut microbiota related metabolites and metabolic health outcomes in young Chinese adults, Nutrition, Metabolism and Cardiovascular Diseases, 2022 https://doi.org/10.1016/j.numecd.2022.10.016 . E-published ahead of print. IF=3.9

8. Xu, K, Shi, L, Zhang, B, Mi, B, Yang, J, Sun, X, Liao X, Dai X, Zeng L, Liu X*, Yan, H*. Distinct metabolite profiles of adiposity indices and their relationships with habitual diet in young adults. Nutrition, Metabolism and Cardiovascular Diseases. 2021, https://doi.org/10.1016/j.numecd.2021.03.025  E-published ahead of print. IF=3.9

9. Liu X*, Shi L, Dai X*, Chen H, Zhang C, Wang P, Wu Q, Zeng L, Yan H, Plasma metabolites mediate the association of coarse grain intake with blood pressure in hypertension –free adults. Nutrition Metabolism and Cardiovascular Diseases. 2020 Aug;30(9):1512-19. IF=3.9


联系方式

电子邮箱xinliu@xjtu.edu.cn

联系电话:029-82655108

个人主页:xinliu.gr.xjtu.edu.cn

联系地址:中国西部科技创新港泓仁楼(21号楼)3047室;西安市雁塔西路76号卫法楼2


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