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*研究领域:
牙体牙髓根尖周组织疾病的病因、治疗与预防
*个人及工作简历:
侯铁舟,博士,主任医师。1987年毕业于西安交通大学。现任国际牙医师学院中国区院士,中华口腔医学会牙体牙髓病学专委会常委,陕西省口腔医学会常务理事、牙体牙髓病学专委会前任主任委员,陕西省医学会激光分会副主任委员。先后从事龋病和非龋性疾病的病因、预防及治疗研究,牙体组织断裂及预防研究,牙髓及牙周干细胞生物学研究。
*科研项目:
1.集落刺激因子(CFS-1)信号通路在雌激素根尖周炎“骨保护效应”中的调控作用及机制研究
2.基于氧化应激-焦亡探讨根尖周炎骨破坏机制及中药干预
*学术及科研成果、论文:
科研成果
中华人民共和国卫生部科学技术进步奖:人牙釉质和牙骨质获得性膜的实验研究
国家发明专利
一种用于牙尖斜度测量的装置ZL201510053508.2
论文
1.Ma J,Liu F,Liu P,Dong YY,Chu Z,Hou TZ,Dang YH. Impact of early developmental fluoride exposure on the peripheral pain sensitivity in mice[J]. Int.J.Devl Neuroscience.2015,47:165-171
2.Hou T,Gao L,Zheng J,Liu Z,Wu C,Liu Q,Wu S,Guo X. Matrix metalloproteinase-1 gene polymorphisms and periodontitis susceptibility:A meta-analysis based on 11 case-control studies[J]. Gene.2013,521:111-115
3.Zheng J,Hou T,Gao L,Wu C,Wang P,Wen Y,Guo X. Association between CD14 gene polymorphism and periodontitis:A meta-analysis[J]. Critical ReviewsTM in Eukaryotic Gene Expression.2013,23:115-123
4.Guan, X., Guan, Y., Shi, C., Zhu, X., He, Y., Wei, Z., Yang, J., & Hou, T. Estrogen deficiency aggravates apical periodontitis by regulating NLRP3/caspase-1/IL-1β axis. American journal of translational research. 2020,12(2), 660–671
5.Xiangyao Tong, Siyu Hou, Mei Ma, Lu Zhang, Rui Zou,Tiezhou Hou, Lin Niu.The integration of transcriptome-wide association study and mRNA expression profiling data to identify candidate genes and gene sets associated with dental caries.Archives of Oral Biology,Volume 118:104863,2020
6.Zheng, J., Zhu, X., He, Y., Hou, S., Liu, T., Zhi, K., Hou, T. and Gao, L. CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia. Ann. N.Y. Acad. Sci., 2021, 1485: 56-70.
*联系方式:
联系电话:13152150126
电子邮箱:tiezhou@mail.xjtu.edu.cn
联系地址:西安市西五路98号