安晶


 

姓名:安晶

职称:副教授

学位:博士

单位:西安交通大学医学部基础医学院神经生物学系

电话:82655428

邮箱:anjing@mail.xjtu.edu.cn

 

研究领域或方向

(1)中枢神经损伤与修复;

(2)遗传性视觉疾病的致病机理及治疗

工作经历

2019.05~ 西安交通大学,基础医学院神经生物学研究所,副教授

2015.12~ 2019.05 西安交通大学,基础医学院神经生物学研究所,讲师

2012.09~ 2015.11 第四军医大学, 西京医院眼科,主治医师

2011.09~ 2015.11 第四军医大学, 航空航天医学系临床教研室,讲师

科研项目

1.国家自然科学基金面上项目,82271386,Fgfr3调控Iigp1+星形胶质细胞减轻感染性中枢神经损伤的作用及机制,20230101-20261231,52万元,主持

2. Newton Fund, Academy of Medical Society,Newton International fellowship, NIF\R1\181649, Towards CRISPR/Cas9 - mediated gene correction for inherited retinal disease, 201903~202102,66,000 ponds,Principle Applicant

3.国家自然科学基金青年科学基金项目,81500724,靶向电转染Cacna1f基因对先天性静止性夜盲大鼠视觉信号转导转归的研究、2016.01~2018.12,21.5万元,主持

4.中国博士后科学基金,2016M590952,微环境对Cacna1f突变大鼠视细胞突触重塑的影响,2016.01~2017.12,8万元,主持

5.陕西省社会发展领域科技攻关项目,2016SF-063,和血明目片对视网膜分支静脉阻塞大鼠模型的视觉功能保护作用的研究,2016.01~2017.12,5万元,主持

6.陕西省博士后科学基金,2016BSHEDZZ85,细胞及组织环境对Cacnalf突变模型视细胞突触重塑的研究,2016.01~2017.12,5万元,主持

学术科研

致力于视网膜遗传性疾病的研究及治疗,以及神经损伤与修复研究。在此研究基础上获得国家自然科学基金2项,中国博士后科学基金面上项目1项,陕西省科研项目2项,校级科研项目1项。并获得英国皇家学会牛顿国际学者基金1项及“牛顿学者”荣誉称号。参与国家863计划分课题及国家科技课题任务--重大新药创制分课题的研究;参与全军后勤科研“十二五”重大课题的研究,并参与多项国家自然科学基因项目的研究。以第一作者及通讯作者身份发表SCI论文17篇,发表国内核心期刊、源期刊30余篇。获得陕西省科学技术进步奖二等奖1项,陕西高等学校科学奖一等奖1项。指导多项“大学生创新训练项目”及“本科生实验室开放性项目”。参与校级教学改革项目1项。

Jing An, Associate Professor in department of Neurobiology, Xi’an Jiaotong University Health Science Centre. During Aug 2017 to Aug 2018, and Feb 2019 to Mar 2021, worked in Wolfson Institute for Biomedical Research, University College of London, UK, as CSC academic scholar and Newton fellow.

Research interests

1.Central nervous system injury and repair

2.Pathogenesis and treatment of hereditary retinal diseases

Education

2008 - 2011 Ph.D. in Ophthalmology, Fourth Military Medical University

2005 - 2008 Master in Ophthalmology, Fourth Military Medical University

2000 - 2005 Bachelor in Clinical Medicine, Xiangya School of Medicine, Central South University

WorkExperience

2019/05 - present Associate professor, Institute of Neurobiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center

2019/02 - 2021/03 Newton Fellow, Newton International Fellowship, Academy of Medicine Science

2017/08 - 2018/08 CSC academic visitor, Chinese government scholarship, Chinese scholarship council

2015/12 - 2019/04 Lecturer and postdoctoral researcher, Institute of Neurobiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center

2011/09 - 2015/11 Lecturer, Department of Clinical Aerospace Medicine, Fourth Military Medical University

2012/10 - 2015/11 Physician, Department of Ophthalmology, Xijing hospital, Fourth Military Medical University

Grant Support

1.Towards role and mechanism ofIigp1+astrocytes alleviating CNS infection via FGFR3 mediation. 01/2023-12/2026 National Natural Science Foundation of China (82271386). Principal applicant

2.Newton Fund, Towards CRISPR/Cas9 - mediated gene correction for inherited retinal disease. 03/2019~02/2021Academy of Medical SciencesNewton International fellowship(NIF\R1\181649). Principle Applicant.

3.Gene therapy following electroporation ofCacna1fin retina of rat with congenital stationary night blindness. 01/2016-12/2018 National Natural Science Foundation of China (81500724). Principal applicant

4.Effect of microenvironment on synaptic remodeling of rat withCacna1fmutation. 01/2016-12/2017. China Postdoctoral Science Foundation (2016M590952). Principal applicant

5.Therapeutic effect of Traditional Chinese Medicine on a branch retinal vein occlusion rat model. 01/1016-12/2017 Shaanxi Province Programs for Social Development of Science and Technology (2016SF-063). Principal applicant

6.Synaptic remodeling of visual cells in different celland tissue environments in rat model withCacna1fmutation. 01/1016-12/2017 Postdoctoral Science Foundation of Shaanxi Province(2016BSHEDZZ85). Principal applicant

 


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