叶峰

主任医师,博士生导师。

个人及工作简历

2016-2017美国霍普金斯大学和俄克拉荷马大学胃肠动力研究室访问学者.

参与“十一五”、“十二五”、“十三五”感染病重大项目3项,国家自然科学基金及省部基金多项。

中华中医药学会肝胆病分会委员,中华医学会感染病分会青年委员,中华医学会肝病学会肝衰竭学组委员,中华医学会肝病学会肝纤维化学组委员,陕西省性病委员大学生健康教育与促进委员会主任委员、陕西省性病委员会青年专家委员会副主任委员,陕西省感染病学会青年委员会副主任委员,西安市感染病学会常委。国家药审中心外聘专家。

荣誉:陕西省科学技术进步奖1等奖1项。

研究领域(方向)

(1)医工结合新材料治疗感染性疾病

(2)HBV的母婴传播和脂肪肝以及肝衰竭的中西医结合治疗。

科研项目

(1)科技部,国家重大传染病专项,十三五子课题,2017ZX10203201-004,重型乙型肝炎(肝衰竭)诊疗新技术新设备新方法研究及应用(胃肠功能紊乱诊疗新技术),2017-07至2022-07,40.06万,完成,主持

(2)西安交通大学第一附属医院,临床研究项目,XJTU1AF-CRF-2020-018,丙酚替诺福韦(TAF))长期治疗慢性乙型肝炎合并脂肪肝患者的过程中对脂肪肝的影响,2020-07至2023-07,5万元,在研,主持。

(3)陕西省中医药管理局中医药研究项目,HEMM光动力治疗重度痤疮。陕西省中医药管理局,2021至2023,5万元,主持

(4)陕西省科学技术厅,陕西省自然科学基础研究计划,面上项目,2020JM-399,十二指肠电刺激治疗非酒精性脂肪肝的疗效及机制研究,2019-07至2022-07,3万元,在研,主持

学术及科研成果、专利、论文

1.Feng G, Zhang X, Zhang L, Liu WY, Geng S, Yuan HY, Sha JC, Wang XD, Sun DQ, Targher G, Byrne CD, Zheng TL,Ye F(共同通讯), Zheng MH, Chai J; CHESS-MAFLD consortium. Novel urinary protein panels for the non-invasive diagnosis of nonalcoholic fatty liver disease and fibrosis stages. Liver Int. 2023 Mar 16.

2.Ye F, Zhao W, Yang X, Zhang X, An X, Zhu R, Chen Y, Liu X, Li J, Li K, Zheng J, Lin S, Shi L. The decline of HBV RNA associated with HBeAg seroconversion and double-negative HBV DNA and RNA in chronic hepatitis B patients who received entecavir therapy: a 10-year retrospective cohort study. Ann Transl Med. 2022 Aug;10(16):897.

3:Feng G, He N, Xia HH, Mi M, Wang K, Byrne CD, Targher G, Yuan HY, Zhang XL, Zheng MH,Ye F(通讯作者). Machine learning algorithms based on proteomic data mining accurately predicting the recurrence of hepatitis B-related hepatocellular carcinoma. J Gastroenterol Hepatol. 2022 Nov;37(11):2145-2153.

4: Cui Z, Zhang M, Geng S, Niu X, Wang X, Zhu Y,Ye F(通讯作者), Liu C. Antifungal Effect of Antimicrobial Photodynamic Therapy Mediated by Haematoporphyrin Monomethyl Ether and Aloe Emodin on Malassezia furfur . Front Microbiol. 2021 Nov 16;12:749106

5: Zhang M, Cui Z, Wang Y, Ma W, Ji Y, Ye F,Feng Y(共同通讯), Liu C. Effects of sub-lethal antimicrobial photodynamic therapy mediated by haematoporphyrin monomethyl ether on polymyxin-resistant Escherichia coli clinical isolate. Photodiagnosis Photodyn Ther. 2021.102516. Epub 2021 Aug 29.

6: Zhang X, An X, Shi L, Yang X, Chen Y, Liu X, Li J,Ye F(共同通讯), Lin S. Baseline quantitative HBcAb strongly predicts undetectable HBV DNA and RNA in chronic hepatitis B patients treated with entecavir for 10 years. Sci Rep. 2021 Jun 28;11(1):13389.

7:Zhao W, Liu Y, Zhang M, Cui Z, Qu Z, Li Y, Wan M, Wang W, Chen Y, Shi L, Li J, Ye F(通讯作者). Lipid safety of tenofovir alafenamide during 96-week treatment in treatment-naive chronic hepatitis B patients. Front Med (Lausanne). 2024;11:1399665.

8:Ye F; Liu Y#; Li S; Zhang S; Foreman RD; Chen JD; Sacral nerve stimulation increases gastric accommodation in rats: a spinal afferent and vagal efferent pathway,Am J Physiol Gastrointest Liver Physiol, 2020,318(3):574-581.

9:Liu Y#;Ye F(通讯作者); Zhang S; Li S, Chen J; Characteristics of myoelectrical activities along the small intestine and their responses to test meals of different glycemic index in rats.Am J Physiol Regul Integr Comp Physiol, 2020,318(5): 997-1003.

10:Pan T; Liu X; Liu C; Li J; Ma W; Qin Y; Chen Y; Lin S;Ye F(通讯作者); Evaluation of the photodynamic efficacy and effects of haematoporphyrin monomethyl ether on Trichophyton rubrum microconidia in vitro, Mycoses, 2020 Aug 11.

11:Li S#;Ye F(通讯作者); Farber JP; Linderoth B; Zhang T; Gu JW; Moffitt M; Garrett K; Chen J; Foreman RD; Dependence of c-fos Expression on Amplitude of High-Frequency Spinal Cord Stimulation in a Rodent Model,Neuromodulation, 2019, 22 (2):172-178.

12:Chen Y; Kong Y; Shi L; Zhang X; Yang X; Liu X; Lin S;Ye F(通讯作者); Study of the distribution of hepatitis B immunoglobulin in pregnant mice using small-animal imaging technology,J Med Virol. 2019,91(10):1811-1817.

13:Ye F#; Liu Y#; Li S; Chen JDZ; Hypoglycemic Effects of Intestinal Electrical Stimulation by Enhancing Nutrient-Stimulated Secretion of GLP-1 in Rats,Obes Surg, 2018, 28(9): 2829-2835.

14: Zhang Q, Hu Y, Wei P, Shi L, Shi L, Li J, Zhao Y, Chen Y, Zhang X,Ye F, LiuX, Lin S. Identification of hub genes for adult patients with sepsis via RNA sequencing. Sci Rep. 2022 Mar 24;12(1):5128. doi: 10.1038/s41598-022-09175-z.Erratum in: Sci Rep. 2022 Apr 13;12(1):6211.

15: Wang W, Liu X, Wei P, Ye F, Chen Y, Shi L, Zhang X, Li J, Lin S, Yang X. SPP1 and CXCL9 Promote Non-alcoholic Steatohepatitis Progression Based on Bioinformatics Analysis and Experimental Studies. Front Med (Lausanne).2022 Apr 19;9:862278.

16: Yang X, Wang W, Fan W, Cai L,Ye F, Lin S, Liu X. Hereditary Spherocytosis With Liver Transplantation After Cirrhosis: A Case Report. Front Med (Lausanne). 2022 Feb 11;9:823724.

17: Chen Y, Zhang X, Shi L, Yang X, Liu X,Ye F, Lin S. Role-playing: an Effective Method for Clinical Novitiate Teaching of Infectious Diseases. Med Sci Educ. 2020 Oct 30;31(1):53-57.

18: Lin S, Wang W, Shi L, Yang X, Chen Y, Liu X, Li J,Ye F, An X, Zhang X. Severe Vitamin D Deficiency Is Strongly Associated with Liver Dysfunction and Disease Severity in Hepatitis B Virus Related Cirrhosis and Liver Failure Patients. J Nutr Sci Vitaminol (Tokyo). 1

19:Liu Y; Zhang S;Ye F; Yin J; Li S; Chen JDZ; Ameliorating effects and mechanisms of chronic electroacupuncture at ST36 in a rodent model of dyspepsia induced by cisplatin,Neurogastroenterol Motil, 2019, 31(1): e13474.

20:Zhang S; Liu Y; Li S;Ye F; Foreman RD; Chen JDZ; Effects of electroacupuncture on stress-induced gastric dysrhythmia and mechanisms involving autonomic and central nervous systems in functional dyspepsia. Am J Physiol Regul Integr Comp Physiol,2020,319(1):R106-R113.

21:Liu X; Yang X; Han L;Ye F; Liu M; Fan W; Zhang K; Kong Y; Zhang J; Shi L; Chen Y; Zhang X; Lin S; Pterostilbene alleviates polymicrobial sepsis-induced liver injury: Possible role of SIRT1 signaling,Int Immunopharmacol, 2017 ,49:50-59.

22:Yang X; Chen Y; Zhang J; Tang T; Kong Y;Ye F; Zhang X; Liu X; Lin S; Thymosin α1 treatment reduces hepatic inflammation and inhibits hepatocyte apoptosis in rats with acute liver failure,Exp Ther Med, 2018 ,15(4):3231-3238.

23:Zheng Nanning*; Du Shaoyi*; Wang Jianji; Zhang He; Cui Wenting; Kang Zijian;Yang Tao; Lou Bin; Chi Yuting; Long Hong; Ma Mei; Yuan Qi; Zhang Shupei; Zhang Dong;Ye Feng; and Xin Jingmin; Predicting COVID-19 in China Using Hybrid AI Model,IEEE Transactions on Cybernetics, 2020,50(7):2891-2992

24:Zhang J, Wang Y, Fan M, Guan Y, Zhang W, Huang F, Zhang Z, Li X, Yuan B, Liu W, Geng M, Li X, Xu J, Jiang C, Zhao W,Ye F,Zhu W, Meng L, Lu S, Holmdahl R. Reactive oxygen species regulation by NCF1 governs ferroptosis susceptibility of Kupffer cells to MASH. Cell Metab. 2024 Aug 6;36(8):1745-1763.e6.

联系方式

电子邮箱:yefeng.jiaotong@163.com

联系电话:18991232860

个人主页:jdyfy.com/xjtu.edu.cn

联系地址:陕西省西安市雁塔西路277号


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