孙祺

研究领域(方向)

1)胃癌,(2)结直肠癌,(3)整合素,(4)肿瘤转移与靶向治疗,(5)微创外科


个人及工作简历

外科学博士,美国加州大学博士后,美国加州大学Moores癌症中心高级访问学者,副教授,博士研究生导师,指导硕士生6人,博士生5人。

2023年度陕西省“青年科技新星”人才,入选西安交通大学第一附属医院首届优青培育计划、优秀教师。担任中国抗癌协会肿瘤胃肠病学专委会青年联盟副主任委员,美国癌症研究协会AACR会员,陕西省医师协会结直肠肛门外科分会委员,陕西省抗癌协会软组织肿瘤和肉瘤专委会委员。

主持国家自然科学基金2项,获中国博士后科学基金特别资助、一等资助,陕西省博士后科学基金一等资助。担任SCI期刊《Military Medical Research》科学编辑,《Frontiers in Oncology》客座主编。以第一或通讯作者发表医学SCI期刊论文20余篇,获省级高等学校科学技术奖本科高校类一等奖,合译临床专著1部。


科研项目

近5年主持国家级及省部级课题7项,校级课题2项

1)国家自然科学基金面上项目  82073271

2)国家自然科学基金青年基金  81702362

3)中国博士后科学基金特别资助  2019T120922

4)中国博士后科学基金一等资助 2018M631176

5)陕西省博士后科学基金一等资助(2018BSHYDZZ49

6)陕西省创新人才攀登工程 2023SR5078


学术及科研成果、专利、论文

作为第一/通讯作者发表SCI论文18篇。

1) Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis. Journal of Clinical Investigation. 2018;128(1):531-544

IF: 19.46JCR Q1Feature Article “亮点文章

2) Pontin Acts as a Potential Biomarker for Poor Clinical Outcome and Promotes Tumor Invasion in Hilar Cholangiocarcinoma. Biomed Res Int. 2018 May 13;2018:6135016

3) Combined Bcl-2/Src inhibition synergize to deplete stem-like breast cancer cells. Cancer Letters. 2019 Aug 10;457:40-46 IF: 9.76JCR Q1

4) Interleukin-6 Promotes Epithelial-Mesenchymal Transition and Cell Invasion through Integrin β6 Upregulation in Colorectal Cancer. Oxid Med Cell Longev. 2020 Aug 13;2020:8032187 IF: 7.31

5) Integrin αvβ6 predicts poor prognosis and promotes resistance to cisplatin in hilar cholangiocarcinoma. Pathol Res Pract. 2020 Jul;216(7):153022

6) Development of a novel autophagy-related gene prognostic signature for gastric cancer. Transl Cancer Res. 2021 Jun;10(6):2790-2800

7) Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1. NPJ Breast Cancer. 2022 Jan 13;8(1):5  

IF: 7.52JCR Q1Nature合作期刊)

8) Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway. Cells. 2022 Jun 30;11(13):2078 IF: 7.67

9) Development and Validation of a 6-Gene Hypoxia-Related Prognostic Signature For Cholangiocarcinoma. Front Oncol. 2022 Jul 18;12:954366 IF: 6.2

10) Comprehensive analysis of the prognostic value and immune infiltration of FGFR family members in gastric cancer. Front Oncol. 2022 Sep 6:12:936952IF: 6.2

11) Expression of Integrin β6 and HAX-1 Correlates with Aggressive Features and Poor Prognosis in Esophageal Squamous Cell Carcinoma. Cancer Manag Res. 2020 Oct 2;12:9599-9608

12) Integrin β6 deficiency protects mice from experimental colitis and colitis-associated carcinoma by altering macrophage polarization. Front Oncol. 2023 May 8;13:1190229IF: 5.7

13) Breast cancer stem cells tolerate chromosomal instability during tumor progression via c-Jun/AXL stress signaling. Heliyon. 2023 Sep 14;9(9):e20182Cell旗下期刊)

14) Integrated Multi-omics Analyses Identify CDCA5 as a Novel Biomarker Associated with Alternative Splicing, Tumor Microenvironment, and Cell Proliferation in Colon Cancer Via Pan-cancer Analysis. J Cancer. 2024 Jan 1;15(3):825-840

15) Development of fatty acid metabolism score based on gene signature for predicting prognosis and immunotherapy response in colon cancer. Clin Transl Oncol. 2024 Mar;26(3):630-643

16) Expression patterns of E2Fs identify tumor microenvironment features in human gastric cancer. PeerJ. 2024 Feb 13;12:e16911

17) Integrative Multiomics Profiling Unveils the Protective Function of Ulinastatin against Dextran Sulfate Sodium-Induced Colitis. Antioxidants. 2024 Feb 8;13(2):214IF: 7.0,最具学术影响力期刊)

18) Comprehensive analysis reveals TSPEAR as a prognostic biomarker in colorectal cancer. J Cancer. 2024 Jan 1;15(3):809-824




联系方式

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联系电话:15529608720

个人主页:http://www.en.jdyfy.com/info/1011/2767.htm

联系地址:陕西省西安市雁塔西路277号西安交通大学第一附属医院外科大楼8  


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