王彬,博士,博士研究生导师,副研究员,主治医师
研究领域(方向)
(1)乳腺癌的靶向治疗耐药及新靶点药物设计(2)乳腺癌基因组不稳定
个人及工作简历
2021/01-至今,西安交通大学,第一附属医院乳腺外科,博士研究生导师,副研究员,主治医师
2016/12-2020.12,西安交通大学,第一附属医院乳腺外科,硕士研究生导师,助理研究员,住院医师
2014/02-2016/01,美国西南医学中心泌尿外科研究所,联合培养博士生,合作导师:Jer-Tsong Hsieh
2007/09-2016/12,西安交通大学,医学部,首批8年制,导师:贺大林
科研项目
1.国家自然科学基金面上项目,8217101543,《SF3B1-K700E/NONO复合物通过雌激素非依赖途径激活ER导致乳腺癌内分泌耐药机制研究》,2022/01-2025/12,55万元,在研,主持。
2.国家自然科学基金青年项目,81702633,《PROX1调控β-catanin在乳腺癌淋巴转移中的作用和机制研究》,2018/01-2020/12,20万元,结题,主持。
3.陕西省科技厅重点研发-一般项目,2022SF-370,《抑制BRCA1/BARD1结合在乳腺癌卡铂增敏中的机制研究》,2022/01-2023/12,5万元,在研,主持。
学术及科研成果、专利、论文
(1) lizhe Zhu#, Qi Tian#, Huan Gao, Kaijie Wu, Bo Wang, Guanqun Ge, Siyuan Jiang, Ke Wang, Can Zhou, Jianjun He, Peijun Liu, Yu Ren,Bin Wang. PROX1 promotes breast cancer invasion and metastasis through WNT/beta-catenin pathway via interacting with hnRNPK. International Journal of Biological Science.2022, 18(5). 2032-2046. IF=10.75
(2)Bin Wang#, U-Ging Lo#, Kaijie Wu#, Payal Kapur, Xiangyang Liu, Jun Huang, Wei Chen, Elizabeth Hernandez, John Santoyo, Shi-Hong Ma, Rey-Chen Pong, Dalin He*, Yi-Qiang Cheng*, and Jer-Tsong Hsieh*. Developing new targeting strategy for androgen receptor variants in castration resistant prostate cancer. International Journal of Cancer, 2017,141:2121-2130. IF=7.32
(3)Lizhe Zhu, Qi Tian, Siyuan Jiang, Huan Gao, Shibo Yu, Yuhui Zhou, Yu Yan, Yu Ren, Jianjun He*,Bin Wang*. A Novel Ferroptosis-Related Gene Signature for Overall Survival Prediction in Patients With Breast Cancer. Frontiers in Cell Development Biology. 2021, 9: 670184. IF=6.08
(4) Lizhe Zhu#, Wei Wu#, Siyuan Jiang, Shibo Yu, Yu Yan, Ke Wang, Jianjun He, Yu Ren*,Bin Wang*. Pan-Cancer Analysis of the Mitophagy-Related Protein PINK1 as a Biomarker for the Immunological and Prognostic Role. Frontiers in Oncology, 2020, 10: 569887. IF=5.74
(5)Bin Wang#, Shiqi Wu#, Yong Fang, Guangxi Sun, Dalin He, Jer-Tsong Hsieh, Xinyang Wang, Hao Zeng, Kaijie Wu*. The AKR1C3/AR-V7 complex maintains CRPC tumour growth by repressing B4GALT1 expression. Journal of Cellular and Molecular Medicine. 2020, 24(20): 12032-12043. IF=5.30
联系方式
电子邮箱:february111@163.com
联系电话:13669242228
个人主页:无
联系地址:陕西省西安市西安交大第一附属医院乳腺外科