【研究领域（方向）】
（1）儿童癫痫发作的检测与预测
（2）遗传性癫痫的发病机制研究
【个人及工作简历】
1.学习经历
1999/09-2006/06吉林大学白求恩医学部 临床医学七年制 硕士
2010/09-2017/09西安交通大学，药理学，博士毕业
2019.3-2020.7美国哈佛医学院附属波士顿儿童医院Research fellow
2.工作经历
2006.7-2011.5西安交通大学第一附属医院儿科住院医师
2011.6-2018.12西安交通大学第一附属医院儿科主治医师
2019.1-至今 西安交通大学第一附属医院儿科副主任医师
2022.8-至今 西安交通大学第一附属医院儿科副主任
【科研项目近5年主持项目】
1.陕西省科学技术厅，重点研发计划项目，2024SF-YBXM-298,应用深度学习多模态检测儿童癫痫发，2024-01至2025-12，6万元，主持
2.中国抗癫痫协会，青峰癫痫患者管理基金，CQ-B-2021-10，应用深度迁移学习视频检测儿童癫痫发作的研究，2022-01至2023-12，5万元，主持
3.陕西省科学技术厅，重点研发计划项目，2018SF-096，短程强的松早期添加治疗Lennox-Gastaut综合征的临床疗效与安全性研究，2018-07至2020-06，5万元，主持
【学术及科研成果、专利、论文在国内外学术刊物发表论文情况】
发表SCI 9篇：
[1]Halimeh M,Yang Y, Sheehan T, et al. Wearable device assessments of antiseizure medication effects on diurnal patterns of electrodermal activity, heart rate, and heart rate variability[J]. Epilepsy Behav, 2022, 129: 108635. (IF:2.937)
[2]Yang Y.Video-based Detection of Generalized Tonic-clonic Seizures Using Deep Learning. [J]. IEEE J Biomed Health Inform, 2021, 25(8): 2997-3008. (IF: 7.021)
[3]El, Atrache R, Tamilia, E, Amengual-Gual, M, Mohammadpour, Touserkani F,Yang, Y, Wang, X, Ufongene, C, Sheehan, T, Cantley, S, Jackson, M, Zhang, B, Papadelis, C, Sarkis, R A, Loddenkemper, T. Association between semiologic, autonomic, and electrographic seizure characteristics in children with generalized tonic-clonic seizures[J]. Epilepsy Behav, 2021, 122: 108228.(IF:2.937)
[4]Yang Y,Fang H L, Zhao Met al. Specific alpha7 nicotinic acetylcholine receptor agonist ameliorates isoproterenol-induced cardiac remodeling in mice through TGF-beta1/Smad3 pathway[J]. Clin Exp Pharmacol Physiol, 2017.44(12): 1192-1200.（IF:2.001)
[5]Yang Y, Li D L, Bi, X Y, Sun, L, Yu, X J, Fang, H L, Miao, Y, Zhao, M, He, X, Liu, J J, Zang, W J. Acetylcholine Inhibits LPS-Induced MMP-9 Production and Cell Migration via the alpha7 nAChR-JAK2/STAT3 Pathway in RAW264.7 Cells [J]. Cell Physiol Biochem, 2015, 36(5): 2025-2038. (IF: 4.652)
[6]Zhao, M, He, X,Yang, Y,Yu, X. J, Bi, X. Y, Yang, Y, Xu, M, Lu, X. Z, Sun, Q, Zang, W. J. Acetylcholine protects mesenteric arteries against hypoxia/reoxygenation injury via inhibiting calcium-sensing receptor [J]. J Pharmacol Sci2015, 127, (4), 481-8. (IF: 2.106)
[7]Wei, X. L, Fang, R. T,Yang, Y, Bi, X. Y, Ren, G. X, Luo, A. L, Zhao, M, Zang, W. J. Protective effects of extracts from Pomegranate peels and seeds on liver fibrosis induced by carbon tetrachloride in rats [J].BMC Complement Altern Med2015, 15, 389. (IF: 1.987)
[8]Miao, Y, Bi, X. Y, Zhao, M, Jiang, H. K, Liu, J. J, Li, D. L, Yu, X. J,Yang, Y, Huang, N, Zang, W. J. Acetylcholine inhibits tumor necrosis factor alpha activated endoplasmic reticulum apoptotic pathway via EGFR-PI3K signaling in cardiomyocytes [J]. J Cell Physiol2015, 230, (4), 767-74. (IF: 4.155)
[9]Liu, J. J, Huang, N, Lu, Y, Zhao, M, Yu, X. J, Yang, Y,Yang, Y,Zang, W. J. Improving vagal activity ameliorates cardiac fibrosis induced by angiotensin II: in vivo and in vitro [J]. Sci Rep2015, 5, 17108. (IF: 5.228)
【联系方式】
电子邮箱：yyhflower@126.com
联系电话：029-85323820
联系地址：陕西省西安市雁塔区雁塔西路277号
