王森

王森 西安交通大学医学部 公共卫生学院 地方病研究所,副教授,硕士生导师

研究领域(方向):

大骨节病发病机制与防治研究,基因通路及网络分析及微量元素与地方病的相关性等。

个人教育及工作简历:

2016/12-2017/12     美国加州大学旧金山分校,访问学者

2014/04 至今 西安交通大学,医学部公共卫生学院,教师

2014/03-2018/04     西安交通大学,医学部公共卫生学院,博士后

2010/09-2014/03     西安交通大学,医学部公共卫生学院,博士

2008/07-2010/08     西安交通大学,第二附属医院,住院医师

2005/09-2008/07     西安交通大学,医学院,硕士

2000/09-2005/07     西安交通大学,医学院,本科

教学及科研成果、专利、论文

1.承担的科研项目

国家自然科学基金委青年基金 胰岛素样生长因子-1通路中的IGFBP2基因及COL2A1基因的选择性剪接在大骨节病发病机制中的作用(81402638 2015/1~2017/12  

2.具有代表性的SCI论文

1). Wang S, Guo X, Wang W, Wang S. Genome-wide study identifies the regulatory gene networks and signaling pathways from chondrocyte and peripheral blood monocyte of Kashin-Beck disease, Genes to cells, 2012, 17(8): 619-632.

2). Wang S, Duan C, Zhang F, Ma W, Guo X. Regulatory gene networks and signaling pathways from primary osteoarthritis and Kashin-Beck disease, an endemic osteoarthritis, identified by three analysis software, Gene, 2013, 512(1): 89-96.

3). Wang S, Duan C, Zhang F, Wang X, Guo X. To screen the effective software for analyzing gene interactions from Kashin-Beck disease genome profiling pathway and network, according to the tool of GeneMANIA, International Journal of Data Mining and Bioinformatics. Int J Data Min Bioinform.2015;12(1):100-114.

4). Wang S, Duan C, Liu H, Shao W, Wu C, Han J, Guo X. The roles of selenium, insulin-like growth factor binding protein 2 and suppressor of cytokine signaling 3 in the pathogenesis of Kashin-Beck disease.Biomarkers. 2016,21(5):409-415.

5). Wang S, Duan C, Zhang F, Wang X, Guo X. The Roles of the Interaction of BCL2-Antagonist/Killer 1, Apoptotic Peptidase Activating Factor 1 and Selenium in the Pathogenesis of Kashin-Beck Disease. Biol Trace Elem Res. 2016,170(1):17-24.

6).Wang S, Lv Y, Wang Y, Du P, Tan W, Lammi MJ, Guo X. Network Analysis of Se-and Zn-related Proteins in the Serum Proteomics Expression Profile of the Endemic Dilated Cardiomyopathy Keshan Disease. Biol Trace Elem Res. 2017.

7).Wang S, Fan Z, Zhou B, Wang Y, Du P, Tan W, Lammi MJ, Guo X. Roles of Glycoproteins in the Diagnosis and Differential Diagnosis of Chronic and Latent Keshan Disease. Molecules. 2017,22(5). E746.

8).Wang S, Yan R, Wang B, Du P, Tan W, Lammi MJ, Guo X. Prediction of co-expression genes and integrative analysis of gene microarray and proteomics profile of Keshan disease. Sci Rep. 2018, 8(1):231.

9)  Wang S, Gao Z, Liu H, Meng P, Wu C, Lammi M, Guo X. Roles of glycoprotein glycosylation in the pathogenesis of an endemic osteoarthritis, Kashin–Beck disease, and effectiveness evaluation of sodium hyaluronate treatment.Turk J Med Sci. 2020, 50(4):1028-1037.

10) Meng P, Zhang F, Zhang Y, Wei H, Tan S, Guo X, Wang S, Yu Y. ADAMTS4 and ADAMTS5 may be considered as new molecular therapeutic targets for cartilage damages with Kashin-Beck Disease. Med Hypotheses. 2020,135:109440.


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