研究领域（方向）：
药物复杂体系成分与活性分析研究
细胞膜蛋白相互作用分析及调控
个人及工作简历（个人受教育及工作经历）：
Ø工作经历：
2025-12至今，西安交通大学，药学院，副教授
2021-12至2025-12，西安交通大学，药学院，助理教授
2021-11至2026-01，西安交通大学，博士后
Ø教育经历：
2016-09至2021-09，西安交通大学，药物分析学，博士
2012-09至2016-06，西安交通大学，药学，学士
主要科研项目
[1]国家自然科学基金委员会，青年科学基金项目，82204336，高效无损整合的细胞膜药物筛选材料及中药中P-gp抑制剂的筛选研究，2023-01至2025-12，30万元，结题，主持
[2]陕西省科学技术厅，陕西省重点研发计划一般项目，2025SF-YBXM-459，高纯度正向固定MMP-14细胞膜药物筛选材料的构建及其天然产物抑制剂筛选研究，2025-06至2027-05，8万元，在研，主持
[3]陕西省人力资源和社会保障厅，陕西省博士后科研项目一等资助，基于磁性纳米粒囊泡的基质金属蛋白酶靶向药物筛选材料制备及应用研究，2024-01至2025-12，8万元，结题，主持
[4]西安市科协，青年人才托举计划，959202413068，工程化调控的细胞膜药物筛选材料构建2024-07至2026-06，0.8万元，结题，主持
学术及科研成果、专利、论文
[1] Zhaojia Wang; Chao Bai; Wenkai Cao; Jiaqi Li; Ruji Xiong;Qi Hu*; Sicen Wang*; Xiaoyu Xie*. Catalytic DNA circuit-driven surface-enhanced Raman scattering amplification enables multiplexed live-cell imaging of receptor crosstalk and feedback regulation,ACS Nano, 2026, 20(1): 1578-1589.
[2]Qi Hu; Wenkai Cao; Jiaqi Li; Zhaojia Wang; Ruji Xiong; Chao Bai; Lanlan Jia*; Xiaoyu Xie*. Integrated DNA logic platform enables tumor-specific EGFR dimerization inhibition and downstream effector interrogation,Chemical Engineering Journal, 2026, 527: 171968.
[3] Lanlan Jia; Jialin Guo; Min Li; Tingting Zhang; Yihan Sun; Yuxin Chen; Xiaoyu Xie;Qi Hu*. A cascaded catalytic hairpin 3D DNA walker-assisted dual-targeting biomimetic sensor for intracellular microRNA imaging.Analyst, 2026, 151(3): 870-877.
[4]Qi Hu; Peishan Li; Wenkai Cao; Jiaqi Li; Zhaojia Wang; Tianze Wang; Xiaoyu Xie*. Assembly of DNA networks on the cell membrane enables confined detection of MMP-9 secretion and evaluation of drug efficacy,Analytical Chemistry, 2025, 97(22): 11745-11753.
[5]Qi Hu; Zhaojia Wang; Jiaqi Li; Wenkai Cao; Peishan Li; Xiaoyu Xie*; Sicen Wang*. Nondestructively assemble cell membrane-coated nanoparticles by host−guest interactions for efficient capture of bioactive compounds.Analytical Chemistry, 2024, 96(43): 17353-17361.
[6]Qi Hu; Lanlan Jia; Peishan Li; Tingting Zhang; Quzha Silang; Xiaoyu Xie*; Sicen Wang*. Boosting integration of cell membrane-nanomaterial hybrids via dextran-mediated dynamic dispersion system to capture bioactive compounds in natural products.Journal of Materials Chemistry B, 2023, 11: 2016-2024.
[7]Qi Hu; Lanlan Jia; Xiaolin Zhang; Aihong Zhu; Sicen Wang*; Xiaoyu Xie*. Accurate construction of cell membrane biomimetic graphene nanodecoys via purposeful surface engineering to improve screening efficiency of active components of traditional Chinese medicine.Acta Pharmaceutica Sinica B, 2022, 12(1): 394-405.
[8]Qi Hu; Xiaolin Zhang; Lanlan Jia; Xueyan Zhen; Xiaoyan Pan; Xiaoyu Xie*; Sicen Wang*. Engineering biomimetic graphene nanodecoys camouflaged with the EGFR/HEK293 cell membrane for targeted capture of drug leads.Biomaterials Science,2020, 8: 5690-5697.
[9]Qi Hu; Yusi Bu; Xueyan Zhen; Ke Xu; Ruifang Ke; Xiaoyu Xie*; Sicen Wang*; Magnetic carbon nanotubes camouflaged with cell membrane as a drug discovery platform for selective extraction of bioactive compounds from natural products.Chemical Engineering Journal, 2019, 364: 269-279.
[10]Qi Hu; Yusi Bu; Ruiqi Cao; Gao Zhang; Xiaoyu Xie*; Sicen Wang*. Stability designs of cell membrane cloaked magnetic carbon nanotubes for improved life span in screening drug leads.Analytical Chemistry, 2019, 91: 13062-13070.
联系方式
电子邮箱：huqi77@xitu.edu.cn
联系电话：18792659109
个人主页：
联系地址：陕西省西安市长安区高桥街道中国西部创新港21号楼5136
