程晓亮




*个人及工作简历

2009/09 – 2013/01,北京大学,药学院药剂学系,博士。

2006/09 – 2009/03,华东理工大学,药学院制药工程系,硕士。

2002/09 – 2006/07,西安交通大学,医学院药学系,学士。

2013/01–至今,西安交通大学第一附属医院药学部。

*研究领域(方向)

分子药剂学 药物动力学

*科研项目

1、国家自然科学青年项目,81503010、靶向肿瘤相关巨噬细胞给药系统的构建和药效评价、主持。

2、陕西省自然科学基金,2016JM8079、氯喹对线粒体靶向性阿霉素脂质体诱导肿瘤细胞和干细胞凋亡的影响、主持。

3、西安交通大学第一附属医院院基金,2014YK10、线粒体靶向性二甲双胍和阿霉素脂质体治疗肿瘤干细胞引起的肿瘤复发和转移研究、主持。

4、陕西省博士后基金、靶向肿瘤相关巨噬细胞给药系统的构建和药效评价、主持。

*学术集科研成果、专利、论文

[1] Xiaoliang Cheng, Kunhong Liu, Yong Liu, Maoyi Wang, Ying Ma. Development and validation of a liquid chromatography/tandem mass spectrometry method for determination of caspofungin in dried blood spots. Rapid Communications in Mass Spectrometry. 2018;32:1068–1074.

[2] Xiaoliang Cheng, Bing Chen, Yuanyuan Pan, Liping Guo, Weiyi Feng*, Yalin Dong*. Simultaneous quantification of 5-aminoimidazole-4-carboxamide-1-β- D-ribofuranoside and its active metabolite 5-aminoimidazole-4-carboxamide- 1-β-D-ribofuranotide in mice plasma by LC-MS/MS. Chromatographia, 2018, 81:157-165.

[3]Xiaoliang Cheng, Chun Zhang, Ying Di, Na Li, Hongping Yao, Yalin Dong. An LC-MS/MS method for quantification of daptomycin in dried blood spot: Application in a pharmacokinetics study in critically ill patients. Journal of Liquid Chromatography & Related Technologies. Accepted.

[4] Meng Lei, Hongping Yao, Yalin Dong, Maoyi Wang, Zheng Wang* & Xiaoliang Cheng*. Development and validation of an LC-MS/MS method for simultaneous quantification of voriconazole and its main metabolite voriconazole N-oxide in human plasma and its clinical application. Journal of Liquid Chromatography & Related Technologies. 2017, 40(20): 1047–1053.

[5] Xiao-liang Cheng, Tian-yan Zhou, Bo Li, Meng-yao Li, Liang Li, Zai-quan Li, Wei Lu*. Methotrexate and 5-aminoimidazole-4-carboxamide riboside exert synergistic anticancer action against human breast cancer and hepatocellular carcinoma. Acta Pharmacologica Sinica, 2013, 34: 951-959.

[6] Xiaoliang Cheng, Liping Guo, Zaiquan Li, Liang Li, Tianyan Zhou*, Wei Lu*. A HPLC method for simultaneous determination of 5-aminoimidazole-4-carboxamide riboside and its active metabolite 5-aminoimidazole-4-carboxamide ribotide in tumor-bearing nude mice plasma and its application to pharmacokinetics study. Journal of Chromatography B, 2013, 915-916: 64-70.

[7] 程晓亮,尤海生,王茂义,董卫华*. LC-MS/MS法同时测定人血浆中紫杉醇和多西他赛的质量浓度. 西北药学杂志, 32(5):580-584.

[8] 张雷,姚鸿萍,程晓亮. LC-MS/MS法同时测定人血浆中万古霉素和去甲万古霉素浓度. 西北药学杂志,接受。

联系电话:029-85323537

电子邮箱:chengxiaoliang@mail.xjtu.edu.cn




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