1989年毕业于西安交通大学医学系临床医学专业,分配至第二附属医院血液科工作至今,先后获硕士、博士学位。现任血液科主任、教授、博士生导师兼任科研部主任。兼陕西抗癌协会副理事,血液肿瘤分会候任主委,陕西省临床免疫学会副主委,陕西省医学会副秘书长,陕西省血液专业常委,西安市血液学会副主委。《西部医学杂志》编委,《浙江大学学报》(医学版)评审专家。第九届陕西省青年科技奖获得者,国家青年科技奖候选人。国家自然科学基金一审评审专家
1急性单核细胞白血病新型分子标志物MLAA-34PCR试剂盒及疫苗的开发应用研究.陕西省科技统筹创新工程计划项目 项目编号NO. 2014TCL03-02 在研
2急性白血病新基因MLAA-34及其多肽疫苗的研究 国家自然科学基金项目编号NO. 81170516 结题
3多发性骨髓瘤血清差异蛋白的筛选及鉴别诊断模型的建立 陕西省科学技术研究发展计划 项目编号NO. 2011K13-027结题
4急性单核细胞白血病新型肿瘤相关分子MLAA-34的研究 国家自然科学基金 项目编号NO.30971284 结题
5急性单核细胞白血病新型肿瘤相关分子MLAA-34的实验研究 陕西省科技研究发展计划 项目编号 NO. 2009K12-01 结题
6联合应用共刺激分子抗白血病作用 陕西省自然科学基金 项目编号2004C260 结题
近期发表的论文:
1.Shen, Y (Shen, Ying)[ 1 ] ; Bai, J (Bai, Ju)[ 1 ] ; He, AL (He, Aili)[ 1,2 ]. Role of mTOR signaling pathway in acute myeloid leukemia. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 卷: 9 期: 2 页: 637-647 出版年: 2016 (通讯作者)
2.Bai, J (Bai, Ju)[ 1 ] ; He, AL (He, Aili)[ 1 ] ; Zhang, WG (Zhang, Wanggang)[ 1 ] ; Yang, Y (Yang, Yun)[ 1 ] ; Wang, JL (Wang, Jianli)[ 1 ] ; Zhang, PY (Zhang, Pengyu)[ 1 ] ; Feng, YD (Feng, Yuandong)[ 1 ] ; Zhang, L (Zhang, Lei)[ 2 ] ; Chen, HL (Chen, Hongli)[ 1 ] ; Wang, XX (Wang, Xiaman)[ 1 ] . Serum Peptidome Based Multiple Myeloma Renal Impairment Biomarker Screening. BLOOD卷: 126 期: 23出版年: DEC 3 2015 (通讯作者)
3.Lei, XR (Lei, Xiao-Ru)[ 1 ] ; Chen, HL (Chen, Hong-Li)[ 1 ] ; Wang, FX (Wang, Fang-Xia)[ 1 ] ; Bai, J (Bai, Ju)[ 1 ] ; He, AL (He, Ai-Li)[ 1 ]. Busulfan plus fludarabine compared with busulfan plus cyclophosphamide as a conditioning regimen prior to hematopoietic stem cell transplantation in patients with hematologic neoplasms: a meta-analysis. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE: 8 期: 8 页: 12064-12075出版年: 2015 (通讯作者)
4.Bai, J (Bai, Ju)[ 1 ] ; He, AL (He, Aili)[ 1 ] ; Zhang, WG (Zhang, Wanggang)[ 1 ] ; Yang, Y (Yang, Yun)[ 1 ] ; Wang, JL (Wang, Jianli)[ 1 ] ; Zhang, PY (Zhang, Pengyu)[ 1 ] ; Feng, YD (Feng, Yuandong)[ 1 ] ; Zhang, L (Zhang, Lei)[ 2 ] ; Chen, HL (Chen, Hongli)[ 1 ] ; Wang, XM (Wang, Xiaman)[ 1 ] . Alterations in a Panel of Serum Peptides Correlate with the Disease States of Multiple Myeloma. BLOOD卷: 126 期: 23出版年: DEC 3 2015 (通讯作者)
1 Bai J, He AL, Zhan, WG, Yang Y , Wang JL, Zhang PY , Zhang Y, Zhang L, Gu LF, Wang J. Serum Platelet Factor 4 Is a Promising Therapeutic Response and Prognostic Marker in Patients with Newly Diagnosed Multiple Myeloma.56th Annual Meeting of the American-Society-of-Hematology: Abstract, BLOOD,2014,124:21 IDS 号:CA9HU(通讯作者)
2 Bai J, He AL, Zhang WG, Wang JL , Yang Y ,Zhang PY, Gu LF, Wang J, Zhang Y,Zhang L . MLAA-34: A New Leukemia-Associated Antigen for Immunotherapy Against Acute Monocytic Leukemia.56th Annual Meeting of the American-Society-of-Hematology,Abstract,BLOOD,2014,124:21. IDS 号:CA9KX(通讯作者)
3 Bai J , He A , Huang C , Yang J , Zhang W , Wang J , Yang Y , Zhang P , Zhang Y , Zhou F. Serum peptidome based biomarkers searching for monitoring minimal residual disease in adult acute lymphocytic leukemia. Proteome Sci 2014 ;12 (1): 49. doi: 10.1186/s12953-014-0049-y(共同通讯作者)
4 Bai J , He A , Zhang W , Huang C , Yang J , Yang Y , Wang J , Zhang Y . Potential biomarkers for adult acute myeloid leukemia minimal residual disease assessment searched by serum peptidome profiling.Proteome Sci 2013 ;11(3) :39 doi: 10.1186/1477-5956-11-39.(共同通讯作者)
5 Aili He, Ju Bai,, Chen Huang , Juan Yang, Wanggang Zhang, Jianli Wang, Yun Yang, Pengyu Zhang, Fuling Zhou. Detection of serum tumor markers in multiple myeloma using the CLINPROT system.International Journal of Hematology,2012,95(6):668-674 DOI 10.1007/s12185-012-1080-3
6 Aili He, Wanggang Zhang, KangLing Xu, Jianli Wang, Yun Yang, Xingmei Chao. Anti-tumor immune responses in immune-reconstituted mice injected with a tumor vaccine. Medical Oncology,2012,29(3):2261-2269 DOI 10.1007/s12032-011-0024-8
7 Aili He, Wanggang Zhang, Yu NiuJianli Wang, Xingmei Chao,Yun Yang.When Should Hemodialysis or Plasma Exchange Be Used to Reduce Early Death Hemophagocytic Lymphohistiocytosis? International Medicinal Journal,2012,19(1):27-30 SCI收录IDS号 929AB
8 Aili He, Wanggang Zhang, Xingmei Cao. EBV Infection Associated Hemophagocytic Syndrome as the First Manifestation of Primary Hepatic Peripheral T-Cell Lymphoma: A Short Report. International Medicinal Journal,2012,
9(1):79-81 SCI收录IDS号 929AB
科技奖励
1 陕西省科学技术奖二等奖(证书未发) 第一完成人 多发性骨髓瘤分子靶点及综合治疗研究
2 陕西高等学校科学技术奖一等奖,证书编号:16017 第一完成人 多发性骨髓瘤分子靶点及综合治疗研究
3 陕西省科技成果奖 证书号09-2-67-R2 二等奖 第二完成人 白血病免疫逃逸机制及逆转研究
4 第九届陕西省青年科技奖 科技标兵 国家青年科技奖 候选人