刘建新

姓名:

刘建新

一级学科:

基础医学   生物学

照片:

研究领域(方向):

1. 癫痫发病机制和治疗

2. 脑损伤与内源性修复

3. 脑肿瘤

个人及工作简历:

2007年12月获西安交通大学医学博士学位,毕业留校,在西安交通大学医学部基础医学院工作至今。教授,博士研究生导师,现任脑科学研究所副所长。

2005年7月-2007年1月在新加坡国立神经科学研究所进行博士课题研究,2009年4月-2010年4月在英国剑桥大学进行博士后研究。

主要科研项目

1. 国家自然科学基金面上项目(81971210)

2. 国家自然科学基金面上项目(31671249)

3. 国家自然科学基金面上项目(81371427)

4. 国家自然科学基金面上项目(81171232)

5. 高等学校博士学科点专项科研基金(新教师类)(20100201120067)

6. 教育部留学回国人员科研启动基金(12回国基金03)

代表性论著、科研获奖、人才称号

1. Xiao   XL, Wu JT, Zhang HZ, Wang YD, Zhang JQ, Liu LF, Yu-Chen, Min-Li, Yang PB, Wu   XL, Liu JX (corresponding author).   The neurotoxic effect of isoflurane on age-defined neurons generated from   tertiary dentate matrix in mice. Brain Behav. 2021, 11(1):e01949.

2. Xiao   XL, Wu XL, Yang PB, Hu HB, Chen Y, Min-Li, Si KW, Wu F, Liu JX (corresponding author). Status epilepticus induced Gadd45b   is required for augmented dentate neurogenesis. Stem Cell Res. 2020,   49:102102.

3. Xiao   XL, Wu XL, Tong H, Tan J, Liu LF, Si KW, Peng-Bo-Yang, Ma YB, Zhou JS, Liu JX (corresponding author).   Identification of microRNA-target genes in mice hippocampus at 1 week after   pilocarpine-induced status epilepticus. Biochem Biophys Res Commun. 2020,   531(3):275-281.

4. Iqbal   M, Xiao XL, Zafar S, Yang PB, Si KW, Han H, Liu JX (corresponding author) , Liu Y. Forced Physical Training   Increases Neuronal Proliferation and Maturation with Their Integration into   Normal Circuits in Pilocarpine Induced Status Epilepticus Mice. Neurochem   Res. 2019, 44:2590-2605

5. Zhu K,   Yuan B, Hu M, Li CJ, Xu JH, Feng GF, Liu Y, Liu JX (corresponding author). Ablation of aberrant neurogenesis   fails to attenuate cognitive deficit of chronically epileptic mice. Epilepsy   Res. 2018 , 142:1-8

6. Zhu K,   Hu M, Yuan B, Liu JX (corresponding   author), Liu Y. Aspirin attenuates spontaneous recurrent seizures in the   chronically epileptic mice. Neurol Res. 2017, 7:1-14

7. Zhu K,   Yuan B, Hu M, Feng GF, Liu Y, Liu JX   (corresponding author). Reduced abnormal integration of adult-generated   granule cells does not attenuate spontaneous recurrent seizures in mice.   Epilepsy Res. 2017, 133:58-66

8. Liu JX, Hu   M, Zhu K, Chen XL, Zhang JS, Yuan B, Liu Y. Residual neurogenesis in   chronically epileptic hippocampus of mice. Epilepsy Res. 2016, 127:40-49

9. Liu JX, Cao   X, Liu Y, Tang FR. Altered expression of neuronal CCR6 during pilocarpine   induced status epilepticus in mice. Epilepsy Res. 2016, 126:45-52

10. Hu M,   Zhu K, Chen XL, Zhang YJ, Zhang JS, Xiao XL, Liu JX (corresponding author), Liu Y. Newly generated neurons at   2 months post-status epilepticus are functionally integrated into neuronal   circuitry in mouse hippocampus. Exp Neurol. 2015, 273:273-87

11. Liu JX, Hu   M, Chen XL, XU JH, Yang PB, Zhang JS, Liu Y. Reduced expression of   Phospholipase C beta in hippocampal interneuron during pilocarpine induced   status epilepticus in mice. Neurochem Int. 2014, 68:10-17

12. Liu JX, Cao   X, Liu Y, Tang FR. CCL28 in the mouse hippocampal CA1 area and the dentate   gyrus during and after pilocarpine-induced status epilepticus. Neurochem Int.   2012, 61(7):1094-1101

13. Liu JX,   Pinnock SB, Herbert J. Novel control by the CA3 region of the hippocampus on   neurogenesis in the dentate gyrus of the adult rat. PLoS One. 2011,   6(3):e17562

14. Liu JX, Liu   Y, Tang FR. Pilocarpine-induced status epilepticus alters hippocampal PKC   expression in mice. Acta Neurobiol Exp. 2011, 71(2):220-232

15. Liu JX, Tang   YC, Liu Y, Tang FR. Status epilepticus alters hippocampal PKAβ and PKAγ   expression in mice. Seizure-EUROPEAN JOURNAL OF EPILEPSY. 2010, 19:414-420

16. Liu JX, Tang   YC, Liu Y, Tang FR. mGluR5-PLCβ4-PKCβ2/PKCγ   Pathways in Hippocampal CA1 Pyramidal Neurons in Pilocarpine Model of Status   Epilepticus in mGluR5+/+ and mGluR5-/- Mice. Epilepsy Research,   2008,82(2-3):111-123

17. Liu JX, Cao   X, Tang YC, Liu Y, Tang FR. CCR7, CCR8, CCR9 and CCR10 in the mouse   hippocampal CA1 area and the dentate gyrus during and after   pilocarpine-induced status epilepticus. J Neurochem, 2007,100(4):1072-1088

联系方式

电子邮箱liujianxin@mail.xjtu.edu.cn

联系电话:18092315711

联系地址: 西安市雁塔西路76号,710061

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