代表性论著、科研获奖、人才称号 |
代表性论著： 1. Lei Wang, Jie Liu, Li-Juan Guo, Wang Wang, Yue-Xiu Wang, Zhi-Fei Zhang, Jun Wang, Chen Wang*. MicroRNA expression profile of pulmonary artery smooth muscle cells and the effect of let-7d in chronic thromboembolic pulmonary hypertension. Pulmonary Circulation. 3(3):1-11.2013. 2. Lei Wang, Hui-Li Gan, Yan Liu, Song Gu, Jing Li, Li-Juan Guo, Jie Liu, Ying Wang, Yue-Xiu Wang, Zhi-Fei Zhang, Jun Wang, Chen Wang*. The distinguishing cellular features of pulmonary artery smooth muscle cells from chronic thromboembolic pulmonary hypertension patients. Experimental Lung Research.39(8):349-358. 2013. 3. Xiao-Min Yu, Lei Wang (co-first author), Ji-Feng Li, Jie Liu, Jing Li, Wang Wang, Jun Wang*, Chen Wang*. Wnt5a inhibits hypoxia-induced pulmonary arterial smooth muscle cell proliferation by downregulation of beta-catenin. Am J Physiol Lung Cell Mol Physiol. 304(2): L103-111. 2013. 4.王蕾,于晓敏,李冉,郭益群,刘颖梅,曹彬*.肿瘤坏死因子(TNF)-a拮抗剂相关人肺孢子菌合并EB病毒和巨细胞病毒三重感染1例.中国实用内科学杂志2013,33(2): 129-131 5. Lei Wang, Jie Liu, Wang Wang, Xianmei Qi, Ying Wang, Bo Tian, Huaping Dai, Jing Wang, Wen Ning*, Ting Yang*, Chen Wang*. Targeting IL-17 attenuates hypoxia-induced pulmonary hypertension through downregulation of β-catenin. Thorax. 2019, 74(6):564-578. 6. Lei Wang, Ke Hao, Ting Yang*, Chen Wang*. The role of the lung microbiome in the pathogenesis of chronic obstructive pulmonary disease. Chinese Medical Journal, 2017.9.5, 130 (17): 2107~2111. 7. Lei Wang, Ting Yang*, Chen Wang*. Are statins benifical for the treatment of pulmonary hypertension? Chronic Diseases and Translational Medicine. 2017 Dec 11;3(4):213-220. 8. Hongyan Pang, Lei Wang (co-first author), Jie Liu, Shengfeng Wang, Chen Wang, Yuanhua Yang*, Ting Yang*. The prevalence and risk factors of venous thromboembolism in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease. The Clinical Respiratory Journal. 2018 Nov;12(11):2573-2580. 9.王蕾,杨汀*,王辰. 2017年版慢性阻塞性肺疾病诊断、处理和预防全球策略解读.中国临床医生杂志, 2017,45(1): 104-108. 10. Cazzola Mario,王蕾（译者）,杨汀（审校者）. LABA/LAMA联合用药替代LABA/ICS联合用药可预防或延迟某些慢性阻塞性肺疾病患者的急性加重.英国医学杂志中文版,2017,20(6): 339-340. 11. Liu J, Wang W, Lei Wang, Chen S, Tian B, Huang K, et al. IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1alpha and VEGF Expression in Vascular Endothelial Cells. EBioMedicine. 2018 Jul;33:196-210. 12. Jing Huang; Wei Zhang; Cai-Lian Zhang; Lei Wang*; Interleukin-17 aggravates right ventricular remodeling via activating STAT3 under both normoxia and hypoxia, BMC Cardiovasc Disord, 2021, 21(1): 249 13. Lei Wang, Zhang W, Zhang C, Yan Z, Li S, Zhang C,Li S, Zhang C, Chen Y, Pan Q, Liang X, Chen X*. Prognostic effect of pulmonary hypertension in patients with chronic kidney disease: Univariate and multivariate analyses of factors associated with survival. Front Med (Lausanne). 2022; 9: 972937. 14. Huang J, An Q, Zhang CL, He L, Lei Wang*. Decreased low-density lipoprotein and the presence of pulmonary arterial hypertension among newly diagnosed drug-naïve patients with systemic lupus erythematosus: D-dimer as a mediator. Exp Ther Med. 2022 Jul 27;24(3):595. 15. Lei Wang, Zhang W, Li C, Chen X, Huang J*. Identification of biomarkers related to copper metabolism in patients with pulmonary arterial hypertension. BMC Pulm Med. 2023; 23: 31. 16. Tang X, Wang C, Lei Wang (co-first author), Ren F, Kuang R, Li Z, Han X, Chen Y, Chen G, Wu X, Liu J, Yang H, Liu X, Wang C*, Gao H*, Yin Z*. Aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activity. Acta Pharm Sin B. 2023 Sep;13(9):3930-3944. 17. Lei Wang, Huang J, Zhang R, Zhang M, Guo Y, Liu Y, Li C, Wang W, Ying S, Liu J*, Wang C. Cullin5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF. iScience. 2023 Oct 12;26(11):108199. 18. Shi Y, Liu J, Zhang R, Zhang M, Cui H, Lei Wang, Cui Y, Wang W, Sun Y*, Wang C*. Targeting Endothelial ENO1 (Alpha-Enolase) -PI3K-Akt-mTOR Axis Alleviates Hypoxic Pulmonary Hypertension. Hypertension. 2023 May;80(5):1035-1047. 19. Huang J, An Q, Shi H, Li C, Zhang W, Lei Wang*. Retrospective cohort study of pulmonary arterial hypertension associated with connective tissue disease effect on patients' prognosis. Clin Rheumatol. 2023 Nov;42(11):3131-3142. 20.Chen, X., Z. Yan, Q. Pan, C. Zhang, Y. Chen, X. Liang, S. Li and Lei Wang* (2024). "Bibliometric analysis of T-cells immunity in pulmonary hypertension from 1992 to 2022." Immun Inflamm Dis 12(7): e1280. 21. Lei Wang, Mi Mu, Yu Guo, Jing Huang, Ruoyang Zhang, Muzhi Zhang, Yue Hu, Yanhua Wang, Zhenqiang Gao, Lin Liu, Wang Wang, Yuli Cheng, XinPing Zhu, Jie Liu*, Wei Wang*, Sun Ying.PD-1/PD-L1 Provides Protective Role in Hypoxia-Induced Pulmonary Vascular Remodeling.Hypertension. 2024 Aug;81(8):1822-1836. 22. Huang J, An Q, Ju BM, Zhang J, Fan P, He L, Lei Wang*. Role of vitamin D/VDR nuclear translocation in down-regulation of NF-kappaB/NLRP3/caspase-1 axis in lupus nephritis. Int Immunopharmacol. 2021; 100: 108131. 23. Huang J, Zhang P, An Q, He L, Lei Wang*. New insights into the treatment mechanisms of Vitamin D on PM2.5-induced toxicity and inflammation in mouse renal tubular epithelial cells. Int Immunopharmacol. 2022; 108: 108747. 24.Huang, J., J. Liu, Y. Guo, Z. Gao, W. Shi, Y. Zhang, C. Li, L. Niu and LeiWang*.Smooth muscle NR4A3 upregulation caused by endothelial Caveolin-1 deficiency mediates vascular remodeling and pulmonary hypertension. Free Radic Biol Med.2026;249: 217-229. 25.Jie Liu#, Yu Guo#, Jing Huang#, Zhenqiang Gao, Muzhi Zhang, Yufeng Jia, Huanyu Long, Wenhua Shi, Cong Li, Yonghong Zhang, Shuanying Yang*, Aijun Liu*, Lei Wang*. Adipokine Nesfatin‐1 Mediates Endothelial Dysfunction by Suppressing MEF2B/BMPR1A During Pulmonary Vascular Remodeling. J Am Heart Assoc. 2026;15:e047528. DOI: 10.1161/JAHA.125.047528. 26.黄婧，毛旭，丁朵，王蕾*.维生素D抑制细颗粒物（PM2.5）诱导的A549人肺泡上皮细胞自噬及细胞因子释放；细胞与分子免疫学；2023, 39(1):9-14. 27.黄婧，王蕾*. VitD在降低PM2.5对肺泡上皮细胞毒性中的影响分析.中华肺部疾病杂志. 2022年04期 页码: 481-485. 28.张炜,丁朵,王蕾*.慢性阻塞性肺疾病相关肺动脉高压中肺动脉压力与肺功能的关联性研究.西安交通大学学报:医学版.2022年第6期889-894. 29.王蕾,黄婧*.VitD通过影响VDR/Sirt-1相互作用拮抗低氧诱导的肺动脉内皮细胞凋亡.国际呼吸杂志.2022年第42卷第23期1823-1828. 人才称号： 西安交通大学青年优秀人才A类、陕西省卫健委高层次人才-青年拔尖人才 |
